Alterations in cerebral blood flow produced by hypotension: a comparison of methods.

Alterations in cerebral blood flow produced by controlled episodes of hypotension were studied in 12 juvenile monkeys using a thermocouple techique. The qualitative changes observed agreed closely with those obtained from an earlier study employing [14C]antipyrine autoradiographic methods. The present study extends the validity of the earlier antipyrine investigations by means of the continuous recording. The advantages and disadvantages of the thermocouple technique are examined.