Literature DB >> 8104903

Failure of pulmonary clearance of Rhodococcus equi infection in CD4+ T-lymphocyte-deficient transgenic mice.

S T Kanaly1, S A Hines, G H Palmer.   

Abstract

Pulmonary clearance of Rhodococcus equi requires functional T lymphocytes. In this study, CD8+ T-lymphocyte-deficient transgenic mice cleared virulent R. equi from the lungs while infection in CD4+ T-lymphocyte-deficient transgenic mice persisted. Although both CD4+ and CD8+ T cells function early in pulmonary defense against R. equi, clearance is dependent on CD4+ T lymphocytes.

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Year:  1993        PMID： 8104903      PMCID： PMC281259          DOI： 10.1128/iai.61.11.4929-4932.1993

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  22 in total

1.  Identification of 15- to 17-kilodalton antigens associated with virulent Rhodococcus equi.

Authors:  S Takai; K Koike; S Ohbushi; C Izumi; S Tsubaki
Journal:  J Clin Microbiol       Date:  1991-03       Impact factor: 5.948

2.  Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice.

Authors:  M J Grusby; R S Johnson; V E Papaioannou; L H Glimcher
Journal:  Science       Date:  1991-09-20       Impact factor: 47.728

Review 3.  Rhodococcus equi infection in patients with and without human immunodeficiency virus infection.

Authors:  R L Harvey; J C Sunstrum
Journal:  Rev Infect Dis       Date:  1991 Jan-Feb

Review 4.  Rhodococcus equi: an animal and human pathogen.

Authors:  J F Prescott
Journal:  Clin Microbiol Rev       Date:  1991-01       Impact factor: 26.132

5.  Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells.

Authors:  M Zijlstra; M Bix; N E Simister; J M Loring; D H Raulet; R Jaenisch
Journal:  Nature       Date:  1990-04-19       Impact factor: 49.962

Review 6.  Rhodococcus equi--an easily missed opportunistic pathogen.

Authors:  C Doig; M J Gill; D L Church
Journal:  Scand J Infect Dis       Date:  1991

7.  Electron microscopic investigation of intracellular events after ingestion of Rhodococcus equi by foal alveolar macrophages.

Authors:  M C Zink; J A Yager; J F Prescott; M A Fernando
Journal:  Vet Microbiol       Date:  1987-08       Impact factor: 3.293

8.  The effect of experimental infection with Rhodococcus equi on immunodeficient mice.

Authors:  J A Yager; C A Prescott; D P Kramar; H Hannah; G A Balson; B A Croy
Journal:  Vet Microbiol       Date:  1991-08-30       Impact factor: 3.293

9.  Relapsing systemic infection due to Rhodococcus equi in a drug abuser seropositive for human immunodeficiency virus.

Authors:  G Sirera; J Romeu; B Clotet; P Velasco; J Arnal; F Rius; M Foz
Journal:  Rev Infect Dis       Date:  1991 May-Jun

10.  Germ-line transmission of a disrupted beta 2-microglobulin gene produced by homologous recombination in embryonic stem cells.

Authors:  M Zijlstra; E Li; F Sajjadi; S Subramani; R Jaenisch
Journal:  Nature       Date:  1989-11-23       Impact factor: 49.962
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  21 in total

Review 1.  Macrophage-related diseases of the gut: a pathologist's perspective.

Authors:  Xavier Sagaert; Thomas Tousseyn; Gert De Hertogh; Karel Geboes
Journal:  Virchows Arch       Date:  2012-05-11       Impact factor: 4.064

2.  Identification of pulmonary T-lymphocyte and serum antibody isotype responses associated with protection against Rhodococcus equi.

Authors:  A Marianela Lopez; Melissa T Hines; Guy H Palmer; Debra C Alperin; Stephen A Hines
Journal:  Clin Diagn Lab Immunol       Date:  2002-11

3.  Early development of cytotoxic T lymphocytes in neonatal foals following oral inoculation with Rhodococcus equi.

Authors:  Seth P Harris; Melissa T Hines; Robert H Mealey; Debra C Alperin; Stephen A Hines
Journal:  Vet Immunol Immunopathol       Date:  2011-03-21       Impact factor: 2.046

4.  Clearance of virulent but not avirulent Rhodococcus equi from the lungs of adult horses is associated with intracytoplasmic gamma interferon production by CD4+ and CD8+ T lymphocytes.

Authors:  Stephen A Hines; Diana M Stone; Melissa T Hines; Debby C Alperin; Donald P Knowles; Linda K Norton; Mary J Hamilton; William C Davis; Travis C McGuire
Journal:  Clin Diagn Lab Immunol       Date:  2003-03

5.  Cytokine induction in murine macrophages infected with virulent and avirulent Rhodococcus equi.

Authors:  S Giguère; J F Prescott
Journal:  Infect Immun       Date:  1998-05       Impact factor: 3.441

6.  Modulation of cytokine response of pneumonic foals by virulent Rhodococcus equi.

Authors:  S Giguère; B N Wilkie; J F Prescott
Journal:  Infect Immun       Date:  1999-10       Impact factor: 3.441

7.  Molecular characterization of a lipid-modified virulence-associated protein of Rhodococcus equi and its potential in protective immunity.

Authors:  C Tan; J F Prescott; M C Patterson; V M Nicholson
Journal:  Can J Vet Res       Date:  1995-01       Impact factor: 1.310

8.  Immunoglobulin G subisotype responses of pneumonic and healthy, exposed foals and adult horses to Rhodococcus equi virulence-associated proteins.

Authors:  Kathleen E Hooper-McGrevy; Bruce N Wilkie; John F Prescott
Journal:  Clin Diagn Lab Immunol       Date:  2003-05

9.  Correlation between antibiotic resistance, phage-like particle presence, and virulence in Rhodococcus equi human isolates.

Authors:  P Nordmann; M Keller; F Espinasse; E Ronco
Journal:  J Clin Microbiol       Date:  1994-02       Impact factor: 5.948

10.  Vaccination of mice with salmonella expressing VapA: mucosal and systemic Th1 responses provide protection against Rhodococcus equi infection.

Authors:  Aline F Oliveira; Luciana P Ruas; Silvia A Cardoso; Sandro G Soares; Maria-Cristina Roque-Barreira
Journal:  PLoS One       Date:  2010-01-13       Impact factor: 3.240
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