Literature DB >> 8104464

Angiosarcoma, porphyria cutanea tarda, and probable chloracne in a worker exposed to waste oil contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin.

R McConnell1, K Anderson, W Russell, K E Anderson, R Clapp, E K Silbergeld, P J Landrigan.   

Abstract

A worker developed angiosarcoma, porphyria cutanea tarda, and skin lesions characteristic of mild chloracne. About 10 years earlier he had been employed at a truck terminal in Saint Louis, Missouri, at a time when it was sprayed with waste oil contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). The occurrence of these three rare conditions in a single exposed worker supports the aetiological relation between environmental exposure to TCDD and the subsequent development of soft tissue sarcoma and porphyria cutanea tarda.

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Year:  1993        PMID: 8104464      PMCID: PMC1012172          DOI: 10.1136/oem.50.8.699

Source DB:  PubMed          Journal:  Br J Ind Med        ISSN: 0007-1072


  21 in total

Review 1.  Environmental chloracne: update and overview.

Authors:  J S Taylor
Journal:  Ann N Y Acad Sci       Date:  1979-05-31       Impact factor: 5.691

Review 2.  Porphyrin metabolism in porphyria cutanea tarda.

Authors:  G H Elder
Journal:  Semin Hematol       Date:  1977-04       Impact factor: 3.851

3.  A health survey of workers in a 2,4-D and 2,4,5-T plan with special attention to chloracne, porphyria cutanea tarda, and psychologic parameters.

Authors:  A P Poland; D Smith; G Metter; P Possick
Journal:  Arch Environ Health       Date:  1971-03

4.  Persistence of TCDD in monkey adipose tissue.

Authors:  W P McNulty; K A Nielsen-Smith; J O Lay; D L Lippstreu; N L Kangas; P A Lyon; M L Gross
Journal:  Food Chem Toxicol       Date:  1982-12       Impact factor: 6.023

5.  Direct spectrofluorophotometric determination of porphyrin in diluted urine.

Authors:  S Schwartz; P Edmondson; B Stephenson; D Sarkar; H Freyholtz
Journal:  Ann Clin Res       Date:  1976

6.  The use of thin layer chromatography in the separation of free porphyrins and porphyrin methyl esters.

Authors:  S G Smith
Journal:  Br J Dermatol       Date:  1975-09       Impact factor: 9.302

7.  Purification and properties of human erythrocyte uroporphyrinogen decarboxylase: immunological demonstration of the enzyme defect in porphyria cutanea tarda.

Authors:  S Sassa; H de Verneuil; K E Anderson; A Kappas
Journal:  Trans Assoc Am Physicians       Date:  1983

8.  Human health effects of 2,4,5-T and its toxic contaminants.

Authors:  R R Suskind; V S Hertzberg
Journal:  JAMA       Date:  1984-05-11       Impact factor: 56.272

9.  Porphyria turcica due to hexachlorobenzene: a 20 to 30 year follow-up study on 204 patients.

Authors:  D J Cripps; H A Peters; A Gocmen; I Dogramici
Journal:  Br J Dermatol       Date:  1984-10       Impact factor: 9.302

10.  The development and prognosis of chronic intoxication by tetrachlordibenzo-p-dioxin in men.

Authors:  J Pazderova-Vejlupková; E Lukás; M Nĕmcova; J Pícková; L Jirásek
Journal:  Arch Environ Health       Date:  1981 Jan-Feb
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  1 in total

Review 1.  Environmental chemical exposures and disturbances of heme synthesis.

Authors:  W E Daniell; H L Stockbridge; R F Labbe; J S Woods; K E Anderson; D M Bissell; J R Bloomer; R D Ellefson; M R Moore; C A Pierach; W E Schreiber; A Tefferi; G M Franklin
Journal:  Environ Health Perspect       Date:  1997-02       Impact factor: 9.031

  1 in total

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