Literature DB >> 8104274

Sulphatide and sulphatide antibodies in insulin-dependent diabetes mellitus.

K Buschard1, K Josefsen, T Horn, P Fredman.   

Abstract

Insulin-dependent diabetes mellitus (IDDM) is associated with neurological disorders. Sulph I, a monoclonal antibody to sulphatide (a neural epitope), stained secretory granules in alpha and beta cells of rat islets of Langerhans, but not exocrine tissue. Sera from 88% of 57 newly diagnosed IDDM patients was anti-sulphatide positive, and 76% were positive 6 months later. All 135 healthy controls were negative. Sulphatide antibody may be an IDDM marker.

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Year:  1993        PMID： 8104274     DOI： 10.1016/0140-6736(93)92697-r

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  14 in total

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Review 2.  Involvement of sulfatide in beta cells and type 1 and type 2 diabetes.

Authors:  K Buschard; M Blomqvist; T Osterbye; P Fredman
Journal:  Diabetologia       Date:  2005-09-06       Impact factor: 10.122

3.  Design of a covalently bonded glycosphingolipid microarray.

Authors:  Emma Arigi; Ola Blixt; Karsten Buschard; Henrik Clausen; Steven B Levery
Journal:  Glycoconj J       Date:  2011-11-22       Impact factor: 2.916

4.  Presence of sulphatide (3'-sulphogalactosylceramide) in pericytes in the choroid layer of the eye: sharing of this glycolipid autoantigen with islets of Langerhans.

Authors:  K Buschard; T Horn; K Aaen; K Josefsen; H Persson; P Fredman
Journal:  Diabetologia       Date:  1996-06       Impact factor: 10.122

Review 5.  Glycosphingolipids as potential diagnostic markers and/or antigens in neurological disorders.

Authors:  P Fredman; A Lekman
Journal:  Neurochem Res       Date:  1997-08       Impact factor: 3.996

6.  T-cell epitope analysis using subtracted expression libraries (TEASEL): application to a 38-kDA autoantigen recognized by T cells from an insulin-dependent diabetic patient.

Authors:  P I Neophytou; B O Roep; S D Arden; E M Muir; G Duinkerken; A Kallan; R R de Vries; J C Hutton
Journal:  Proc Natl Acad Sci U S A       Date:  1996-03-05       Impact factor: 11.205

7.  Sulphatide in islets of Langerhans and in organs affected in diabetic late complications: a study in human and animal tissue.

Authors:  K Buschard; K Josefsen; S V Hansen; T Horn; M O Marshall; H Persson; J E Månsson; P Fredman
Journal:  Diabetologia       Date:  1994-10       Impact factor: 10.122

Review 8.  Multiple genes/multiple autoantigens role in type 1 diabetes.

Authors:  N Abiru; G S Eisenbarth
Journal:  Clin Rev Allergy Immunol       Date:  2000-02       Impact factor: 10.817

9.  Type-specific human papillomavirus detection in cervical smears in Romania.

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Journal:  APMIS       Date:  2010-10-25       Impact factor: 3.205

10.  Self-glycolipids modulate dendritic cells changing the cytokine profiles of committed autoreactive T cells.

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Journal:  PLoS One       Date:  2012-12-20       Impact factor: 3.240
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