Literature DB >> 8103338

Interleukin-12 and its role in the generation of TH1 cells.

G Trinchieri1.   

Abstract

Over the past few years a growing number of new cytokines have been discovered. Here, Giorgio Trinchieri reports on one of these, Interleukin 12, and discusses the significance of the many effects it has on the regulation of immunity and its importance to the generation of TH1 cells.

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Year:  1993        PMID： 8103338     DOI： 10.1016/0167-5699(93)90230-I

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  195 in total

1.  Human major group rhinoviruses downmodulate the accessory function of monocytes by inducing IL-10.

Authors:  J Stöckl; H Vetr; O Majdic; G Zlabinger; E Kuechler; W Knapp
Journal:  J Clin Invest       Date:  1999-10       Impact factor: 14.808

2.  Calorie restriction decreases proinflammatory cytokines and polymeric Ig receptor expression in the submandibular glands of autoimmune prone (NZB x NZW)F1 mice.

Authors:  A R Muthukumar; C A Jolly; K Zaman; G Fernandes
Journal:  J Clin Immunol       Date:  2000-09       Impact factor: 8.317

3.  Altered immune response of interferon regulatory factor 1-deficient mice against Plasmodium berghei blood-stage malaria infection.

Authors:  R S Tan; C Feng; Y Asano; A U Kara
Journal:  Infect Immun       Date:  1999-05       Impact factor: 3.441

4.  T cell-, interleukin-12-, and gamma interferon-driven viral clearance in measles virus-infected brain tissue.

Authors:  Samantha R Stubblefield Park; Mi Widness; Alan D Levine; Catherine E Patterson
Journal:  J Virol       Date:  2011-01-26       Impact factor: 5.103

5.  Inhibition of interleukin-12 expression by alpha-thrombin in human peripheral blood mononuclear cells: a potential mechanism for modulating Th1/Th2 responses.

Authors:  A Naldini; L Aarden; A Pucci; C Bernini; F Carraro
Journal:  Br J Pharmacol       Date:  2003-09-29       Impact factor: 8.739

6.  Interleukin-12 alone can not enhance the expression of the cutaneous lymphocyte associated antigen (CLA) by superantigen-stimulated T lymphocytes.

Authors:  H Sigmundsdóttir; J E Gudjónsson; H Valdimarsson
Journal:  Clin Exp Immunol       Date:  2003-06       Impact factor: 4.330

7.  Interleukin-12 production by human monocytes infected with Mycobacterium tuberculosis: role of phagocytosis.

Authors:  S A Fulton; J M Johnsen; S F Wolf; D S Sieburth; W H Boom
Journal:  Infect Immun       Date:  1996-07       Impact factor: 3.441

8.  Proanthocyanidins inhibit UV-induced immunosuppression through IL-12-dependent stimulation of CD8+ effector T cells and inactivation of CD4+ T cells.

Authors:  Mudit Vaid; Tripti Singh; Anna Li; Nandan Katiyar; Samriti Sharma; Craig A Elmets; Hui Xu; Santosh K Katiyar
Journal:  Cancer Prev Res (Phila)       Date:  2010-11-12

9.  Suppressed cell-mediated immunity and monocyte and natural killer cell activity following allogeneic immunization of women with spontaneous recurrent abortion.

Authors:  U Gafter; B Sredni; J Segal; Y Kalechman
Journal:  J Clin Immunol       Date:  1997-09       Impact factor: 8.317

10.  Inducible interleukin-4-secreting cells provoked in mice during chemical sensitization.

Authors:  R J Dearman; L S Ramdin; D A Basketter; I Kimber
Journal:  Immunology       Date:  1994-04       Impact factor: 7.397
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