Literature DB >> 8103293

Lack of association between bipolar affective disorder and tyrosine hydroxylase DNA marker.

Y Inayama1, H Yoneda, T Sakai, T Ishida, S Kobayashi, Y Nonomura, Y Kono, J Koh, H Asaba.   

Abstract

Sixty-eight patients with bipolar affective disorder and 88 controls were investigated for genetic association of tyrosine hydroxylase (TH) restriction fragment length polymorphisms (RFLPs). No significant association between bipolar affective disorder and TH was found. Thus the hypothesis that TH is involved in the pathogenesis of bipolar affective disorder was not supported.

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Year:  1993        PMID: 8103293     DOI: 10.1002/ajmg.1320480206

Source DB:  PubMed          Journal:  Am J Med Genet        ISSN: 0148-7299


  2 in total

Review 1.  Post-genomic era and gene discovery for psychiatric diseases: there is a new art of the trade? The example of the HUMTH01 microsatellite in the Tyrosine Hydroxylase gene.

Authors:  Rolando Meloni; Nicole Faucon Biguet; Jacques Mallet
Journal:  Mol Neurobiol       Date:  2002 Oct-Dec       Impact factor: 5.682

2.  Molecular linkage studies of bipolar disorder.

Authors:  W H Berrettini
Journal:  Dialogues Clin Neurosci       Date:  1999-06       Impact factor: 5.986

  2 in total

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