Literature DB >> 8103148

Vasculitis and antineutrophil cytoplasmic autoantibodies associated with propylthiouracil therapy.

K M Dolman1, R O Gans, T J Vervaat, G Zevenbergen, D Maingay, R E Nikkels, A J Donker, A E von dem Borne, R Goldschmeding.   

Abstract

Vasculitis is a rare complication of propylthiouracil therapy. Antineutrophil cytoplasmic antibodies (ANCA) have been described in association with several vasculitic disorders. We report detection of ANCA against human neutrophil elastase, proteinase 3, and myeloperoxidase in serum from six patients who developed evidence of vasculitis during propylthiouracil treatment of hyperthyroidism. On withdrawal of the drug ANCA concentrations fell and clinical symptoms resolved completely.

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Year:  1993        PMID： 8103148     DOI： 10.1016/0140-6736(93)91761-a

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  43 in total

1.  Systemic vasculitis: epidemiology, classification and environmental factors.

Authors:  D G Scott; R A Watts
Journal:  Ann Rheum Dis       Date:  2000-03       Impact factor: 19.103

Review 2.  Pathogenesis and treatment of ANCA-associated systemic vasculitis.

Authors:  A D Salama
Journal:  J R Soc Med       Date:  1999-09       Impact factor: 5.344

3.  Drug-induced neutropenia associated with anti-neutrophil cytoplasmic antibodies (ANCA): possible involvement of complement in granulocyte cytotoxicity.

Authors:  T Akamizu; S Ozaki; H Hiratani; H Uesugi; J Sobajima; Y Hataya; N Kanamoto; M Saijo; Y Hattori; K Moriyama; K Ohmori; K Nakao
Journal:  Clin Exp Immunol       Date:  2002-01       Impact factor: 4.330

Review 4.  Methods for the detection of anti-neutrophil cytoplasmic antibodies. Recommendations for clinical use of ANCA serology and laboratory efforts to optimize the informative value of ANCA test results.

Authors:  A Wiik
Journal:  Springer Semin Immunopathol       Date:  2001

Review 5.  Propylthiouracil-induced antineutrophil cytoplasmic antibody-associated vasculitis.

Authors:  Min Chen; Ying Gao; Xiao-Hui Guo; Ming-Hui Zhao
Journal:  Nat Rev Nephrol       Date:  2012-06-05       Impact factor: 28.314

6.  Rational requesting or rationing testing?

Authors:  R J Lock
Journal:  J Clin Pathol       Date:  2004-02       Impact factor: 3.411

Review 7.  Antineutrophil cytoplasmic autoantibodies: how are they detected and what is their use for diagnosis, classification and follow-up?

Authors:  Jan Willem Cohen Tervaert; Jan Damoiseaux
Journal:  Clin Rev Allergy Immunol       Date:  2012-12       Impact factor: 8.667

8.  ANCA-associated diffuse alveolar hemorrhage due to benzylthiouracil.

Authors:  Farah Thabet; Rim Sghiri; Brahim Tabarki; Ibtissem Ghedira; Moncef Yacoub; Ahmed Sahloul Essoussi
Journal:  Eur J Pediatr       Date:  2006-04-19       Impact factor: 3.183

9.  Antineutrophil cytoplasmic antibody-positive vasculitis associated with propylthiouracil therapy.

Authors:  S Dinmezel; C Ogus; T Ozdemir
Journal:  Clin Drug Investig       Date:  2003       Impact factor: 2.859

10.  A review of immunofluorescent patterns associated with antineutrophil cytoplasmic antibodies (ANCA) and their differentiation from other antibodies.

Authors:  J A Savige; B Paspaliaris; R Silvestrini; D Davies; T Nikoloutsopoulos; A Sturgess; J Neil; W Pollock; K Dunster; M Hendle
Journal:  J Clin Pathol       Date:  1998-08       Impact factor: 3.411
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