| Literature DB >> 8102519 |
T Efferth1, T A Dunn, M Berlion, H Langenbahn, E W Pommerenke, M Volm.
Abstract
In a panel of 14 primary cultures of human renal cell carcinomas the reversal of inherent multidrug-resistance by S 9788, a new triazinoaminopiperidine derivative, was analysed. In combination with doxorubicin S 9788 revealed an evident reversal of multidrug resistance in 12 cell cultures. Two cell cultures remained unaffected. An association between reversal and P-glycoprotein (P-170) expression suggests that S 9788 exerts its activity through P-glycoprotein.Entities:
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Year: 1993 PMID： 8102519
Source DB: PubMed Journal: Anticancer Res ISSN： 0250-7005 Impact factor: 2.480