Literature DB >> 8102371

Establishment and characteristics of two new human mammary carcinoma lines serially transplantable in nude mice.

H Naundorf1, I Fichtner, G J Saul, W Haensch, B Büttner.   

Abstract

Two human mammary carcinomas of postmenopausal women were successfully transplanted into nude mice. Both tumours were classified as epidermal-growth-factor-, oestradiol- and progesterone-receptor-negative and c-erbB2-protein-positive. Histological studies of the primary tumours (4000 and 4151) revealed ductal invasive mammary carcinomas. In the first passages the precondition for the growth of breast carcinoma 4000 were pretreatments of the nude mice with oestradiol and peanut oil before transplantation. The mammary carcinomas 4000 and 4151 described here are suitable for in vivo testing of antineoplastic substances and for biological studies.

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Year:  1993        PMID： 8102371     DOI： 10.1007/bf01215983

Source DB:  PubMed          Journal:  J Cancer Res Clin Oncol        ISSN： 0171-5216            Impact factor:   4.553


  16 in total

1.  c-erbB-2 oncogene expression in ovarian cancer.

Authors:  J S Haldane; V Hird; C M Hughes; W J Gullick
Journal:  J Pathol       Date:  1990-11       Impact factor: 7.996

2.  Stimulation of growth of human breast cancer cell lines in culture by linoleic acid.

Authors:  D P Rose; J M Connolly
Journal:  Biochem Biophys Res Commun       Date:  1989-10-16       Impact factor: 3.575

3.  Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene.

Authors:  D J Slamon; G M Clark; S G Wong; W J Levin; A Ullrich; W L McGuire
Journal:  Science       Date:  1987-01-09       Impact factor: 47.728

4.  Growth of normal and neoplastic mouse mammary epithelial cells in primary culture: stimulation by conditioned medium from mouse mammary fibroblasts.

Authors:  J Enami; S Enami; M Koga
Journal:  Gan       Date:  1983-12

Review 5.  Hormonal regulation of c-erbB-2 oncogene expression in breast cancer cells.

Authors:  M De Bortoli; C Dati; S Antoniotti; P Maggiora; M L Sapei
Journal:  J Steroid Biochem Mol Biol       Date:  1992-09       Impact factor: 4.292

6.  Expression of IGF-I and IGF-II mRNA in breast tissue.

Authors:  S Paik
Journal:  Breast Cancer Res Treat       Date:  1992       Impact factor: 4.872

7.  Heterotransplantation of human breast carcinomas in nude mice. Correlation between successful heterotransplants, poor prognosis and amplification of the HER-2/neu oncogene.

Authors:  B C Giovanella; D M Vardeman; L J Williams; D J Taylor; P D de Ipolyi; P J Greeff; J S Stehlin; A Ullrich; R Cailleau; D J Slamon
Journal:  Int J Cancer       Date:  1991-01-02       Impact factor: 7.396

8.  Isolation of the neu/HER-2 stimulatory ligand: a 44 kd glycoprotein that induces differentiation of mammary tumor cells.

Authors:  E Peles; S S Bacus; R A Koski; H S Lu; D Wen; S G Ogden; R B Levy; Y Yarden
Journal:  Cell       Date:  1992-04-03       Impact factor: 41.582

9.  Analysis of insulin-like growth factor I gene expression in malignancy: evidence for a paracrine role in human breast cancer.

Authors:  D Yee; S Paik; G S Lebovic; R R Marcus; R E Favoni; K J Cullen; M E Lippman; N Rosen
Journal:  Mol Endocrinol       Date:  1989-03

Review 10.  Human tumor xenografts in the nude mouse and their value as test models in anticancer drug development (review).

Authors:  B Winograd; E Boven; M W Lobbezoo; H M Pinedo
Journal:  In Vivo       Date:  1987 Jan-Feb       Impact factor: 2.155
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  6 in total

1.  Treatment of experimental brain metastasis with MTO-liposomes: impact of fluidity and LRP-targeting on the therapeutic result.

Authors:  Andrea Orthmann; Reiner Zeisig; Regine Süss; Dorothea Lorenz; Margit Lemm; Iduna Fichtner
Journal:  Pharm Res       Date:  2012-03-08       Impact factor: 4.200

2.  Establishment and characteristics of two new human mammary carcinoma lines in nude mice with special reference to the estradiol receptor status and the importance of stroma for in vivo and in vitro growth.

Authors:  H Naundorf; I Fichtner; B Elbe; G J Saul; W Haensch; W Zschiesche; S Reinecke
Journal:  Breast Cancer Res Treat       Date:  1994       Impact factor: 4.872

3.  Antineoplastic activity of alkylphosphocholines (APC) in human breast carcinomas in vivo and in vitro; use of liposomes.

Authors:  I Fichtner; R Zeisig; H Naundorf; S Jungmann; D Arndt; G Asongwe; J A Double; M C Bibby
Journal:  Breast Cancer Res Treat       Date:  1994       Impact factor: 4.872

4.  Molecular cytogenetic analysis of breast cancer cell lines.

Authors:  J M Davidson; K L Gorringe; S F Chin; B Orsetti; C Besret; C Courtay-Cahen; I Roberts; C Theillet; C Caldas; P A Edwards
Journal:  Br J Cancer       Date:  2000-11       Impact factor: 7.640

5.  Reconstitution of mammary gland development in vitro: requirement of c-met and c-erbB2 signaling for branching and alveolar morphogenesis.

Authors:  C Niemann; V Brinkmann; E Spitzer; G Hartmann; M Sachs; H Naundorf; W Birchmeier
Journal:  J Cell Biol       Date:  1998-10-19       Impact factor: 10.539

6.  Relation of oestradiol-mediated growth stimulation with the expression of c-erbB-2 protein in xenotransplanted oestradiol-receptor-positive and -negative breast carcinomas.

Authors:  H Naundorf; K Parczyk; W Zschiesche; S Reinecke; B Büttner; G J Saul; B Sinn; I Fichtner
Journal:  J Cancer Res Clin Oncol       Date:  1996       Impact factor: 4.322
  6 in total

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