Literature DB >> 8102332

Descriptive analysis of cocaine use of methadone patients.

M Kidorf1, M L Stitzer.   

Abstract

The increasing prevalence of cocaine use among opioid-dependent participants in methadone treatment has been documented, but there is little information about the quantity-frequency aspects of use. This study examined the cocaine use of methadone maintenance patients to determine amounts and patterns of use as well as use in combination with other drugs. Forty-five cocaine using methadone maintenance patients (78% used i.v.) reported their drug use for each day over the past 7 days after receiving information about their most recent urinalysis test results. Average reported use was 0.23 g cocaine/day on 3.4 days/week. Heroin and cocaine were typically used simultaneously, while only a subset of patients (47%) who used alcohol drank within close proximity to cocaine. Patients who used cocaine with alcohol and/or heroin on the same day (N = 28) reported more cocaine use (M = 1.0 g/week) than patients who used cocaine alone (N = 17; M = 0.49 g/week). The results suggest that methadone maintenance patients generally engage in relatively low dose cocaine use, especially when compared to non opioid dependent patients applying to cocaine treatment programs. The study further shows that patients had clear preferences for drug use combinations, which suggests that interventions for cocaine use might focus on modifying drugs used in combination with cocaine.

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Year:  1993        PMID: 8102332     DOI: 10.1016/0376-8716(93)90091-4

Source DB:  PubMed          Journal:  Drug Alcohol Depend        ISSN: 0376-8716            Impact factor:   4.492


  6 in total

1.  Enhancement of cocaine's abuse liability in methadone maintenance patients.

Authors:  K L Preston; J T Sullivan; E C Strain; G E Bigelow
Journal:  Psychopharmacology (Berl)       Date:  1996-01       Impact factor: 4.530

2.  The safety and efficacy of varenicline in cocaine using smokers maintained on methadone: a pilot study.

Authors:  James Poling; Bruce Rounsaville; Kishorchandra Gonsai; Kevin Severino; Mehmet Sofuoglu
Journal:  Am J Addict       Date:  2010 Sep-Oct

3.  Heroin and cocaine co-use in a group of injection drug users in Montréal.

Authors:  Francesco Leri; Jane Stewart; Annie Tremblay; Julie Bruneau
Journal:  J Psychiatry Neurosci       Date:  2004-01       Impact factor: 6.186

Review 4.  Methadone maintenance treatment: an update.

Authors:  G Bertschy
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  1995       Impact factor: 5.270

5.  Changes in substance use in relation to opioid agonist therapy among people who use drugs in a Canadian setting.

Authors:  Huiru Dong; Kanna Hayashi; M-J Milloy; Kora DeBeck; Joel Singer; Hubert Wong; Evan Wood; Thomas Kerr
Journal:  Drug Alcohol Depend       Date:  2020-04-25       Impact factor: 4.492

6.  A randomized investigation of methadone doses at or over 100 mg/day, combined with contingency management.

Authors:  Ashley P Kennedy; Karran A Phillips; David H Epstein; David A Reamer; John Schmittner; Kenzie L Preston
Journal:  Drug Alcohol Depend       Date:  2012-11-26       Impact factor: 4.492

  6 in total

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