Literature DB >> 8101258

Secretion of epidermal growth factor by macrophages associated with breast carcinoma.

C O'Sullivan1, C E Lewis, A L Harris, J O McGee.   

Abstract

By means of a cytokine release assay we have shown that in cell populations derived from primary breast carcinoma, epidermal growth factor (EGF) is secreted by cells with the characteristic morphological and immunophenotypic profile of activated macrophages (positive for CD68, CD16, CD25). EGF secretion was observed in 11 (31%) of 35 primary tumours. Secretion of EGF by normal or malignant epithelial cells was not observed. We found no association between EGF secretion by the primary tumour and recognised clinical indices of prognosis.

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Year:  1993        PMID： 8101258     DOI： 10.1016/0140-6736(93)91348-p

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  48 in total

1.  The expression of interleukin (IL)-17 and IL-17 receptor and MMP-9 in human pituitary adenomas.

Authors:  Lubin Qiu; Dongsheng He; Xiang Fan; Zhi Li; Chuangxin Liao; Yonghong Zhu; Haijun Wang
Journal:  Pituitary       Date:  2011-09       Impact factor: 4.107

Review 2.  Tumor-associated macrophages in breast cancer.

Authors:  Russell D Leek; Adrian L Harris
Journal:  J Mammary Gland Biol Neoplasia       Date:  2002-04       Impact factor: 2.673

3.  Macrophage-tumour cell interactions: identification of MUC1 on breast cancer cells as a potential counter-receptor for the macrophage-restricted receptor, sialoadhesin.

Authors:  D Nath; A Hartnell; L Happerfield; D W Miles; J Burchell; J Taylor-Papadimitriou; P R Crocker
Journal:  Immunology       Date:  1999-10       Impact factor: 7.397

4.  Tumor-associated macrophages are involved in tumor progression in papillary renal cell carcinoma.

Authors:  Carl Ludwig Behnes; Felix Bremmer; Bernhard Hemmerlein; Arne Strauss; Philipp Ströbel; Heinz-Joachim Radzun
Journal:  Virchows Arch       Date:  2013-12-11       Impact factor: 4.064

Review 5.  Altered macrophage differentiation and immune dysfunction in tumor development.

Authors:  Antonio Sica; Vincenzo Bronte
Journal:  J Clin Invest       Date:  2007-05       Impact factor: 14.808

6.  Gene expression analysis of macrophages that facilitate tumor invasion supports a role for Wnt-signaling in mediating their activity in primary mammary tumors.

Authors:  Laureen S Ojalvo; Charles A Whittaker; John S Condeelis; Jeffrey W Pollard
Journal:  J Immunol       Date:  2009-12-16       Impact factor: 5.422

7.  Impact of tumor-associated macrophages in LH(BETA)T(AG) mice on retinal tumor progression: relation to macrophage subtype.

Authors:  Yolanda Piña; Hinda Boutrid; Timothy G Murray; Martine J Jager; Colleen M Cebulla; Amy Schefler; Long V Ly; Armando Alegret; Magda Celdran; William Feuer; Maria-Elena Jockovich
Journal:  Invest Ophthalmol Vis Sci       Date:  2010-01-06       Impact factor: 4.799

8.  The macrophage colony-stimulating factor 1 response signature in breast carcinoma.

Authors:  Andrew H Beck; Inigo Espinosa; Badreddin Edris; Rui Li; Kelli Montgomery; Shirley Zhu; Sushama Varma; Robert J Marinelli; Matt van de Rijn; Robert B West
Journal:  Clin Cancer Res       Date:  2009-02-01       Impact factor: 12.531

Review 9.  Macrophage-targeted photodynamic therapy.

Authors:  T N Demidova; M R Hamblin
Journal:  Int J Immunopathol Pharmacol       Date:  2004 May-Aug       Impact factor: 3.219

Review 10.  The role of macrophages in the development and progression of AIDS-related non-Hodgkin lymphoma.

Authors:  Leanne C Huysentruyt; Michael S McGrath
Journal:  J Leukoc Biol       Date:  2009-12-30       Impact factor: 4.962
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