| Literature DB >> 810057 |
M Ferrarini, A Bargellesi, G Corte, G Viale, B Pernis.
Abstract
Immunofluorescent and "in vitro" biosynthetic techniques have been used to study the connections between the maturation process of human lymphocytes that leads to the appearance of actively secreting cells and a possible switchover from IgD to IgM production, both in homogeneous CLL cell populations and in heterogeneous cell suspensions from tonsils. The results obtained are compatible with the hypothesis that the switchover from IgD to IgM productions can be a clonal maturation phenomenon.Entities:
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Year: 1975 PMID: 810057 DOI: 10.1111/j.1749-6632.1975.tb29174.x
Source DB: PubMed Journal: Ann N Y Acad Sci ISSN: 0077-8923 Impact factor: 5.691