Literature DB >> 8100382

Stimulation of human neutrophil migration by aurothioglucose and thioglucose.

J G Elferink1, B M de Koster.   

Abstract

Migration of human neutrophils was enhanced by aurothioglucose in a concentration-dependent manner. Migration was especially pronounced when the drug was present in the lower compartment of the Boyden chamber, suggesting that the enhancement of migration was chemotactic rather than chemokinetic. Thioglucose followed the same pattern of stimulation as the related gold compound, but the enhancement at the maximally stimulating concentration was less; at higher concentrations thioglucose inhibited random migration.

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Year:  1993        PMID: 8100382     DOI: 10.1007/bf01991162

Source DB:  PubMed          Journal:  Agents Actions        ISSN: 0065-4299


  5 in total

1.  Chrysotherapy. A prospective study.

Authors:  N O Rothermich; V K Philips; W Bergen; M H Thomas
Journal:  Arthritis Rheum       Date:  1976 Nov-Dec

2.  Comparison of auranofin and aurothioglucose in the treatment of rheumatoid arthritis: a single blind study.

Authors:  P L van Riel; L B van de Putte; F W Gribnau; K D Macrae
Journal:  Clin Rheumatol       Date:  1984-03       Impact factor: 2.980

3.  Tiopronin (2-mercaptopropionylglycine) has chemokinetic and chemotactic properties for polymorphonuclear leukocytes.

Authors:  J G Elferink; B M de Koster
Journal:  Immunopharmacology       Date:  1992 Mar-Apr

4.  Stimulation of rabbit polymorphonuclear leukocyte locomotion by D-penicillamine.

Authors:  J G Elferink; B M De Koster
Journal:  Biochem Pharmacol       Date:  1991-10-09       Impact factor: 5.858

5.  Leukocyte locomotion and chemotaxis. New methods for evaluation, and demonstration of a cell-derived chemotactic factor.

Authors:  S H Zigmond; J G Hirsch
Journal:  J Exp Med       Date:  1973-02-01       Impact factor: 14.307

  5 in total

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