| Literature DB >> 8098688 |
P W Albro1, J T Corbett, J L Schroeder.
Abstract
1. Earthworms can hydrolyze di-(2-ethylhexyl) phthalate (DEHP) to mono-2-ethylhexyl phthalate (MEHP) and phthalic acid (PA). 2. They apparently cannot produce the side-chain-oxidized derivatives of MEHP that constitute the major DEHP metabolites in higher animals. 3. With the assistance of intestinal bacterial Pseudomonas, the worm-derived PA is degraded through protocatechuic and beta-carboxymuconic acids to CO2. 4. There is an indication of a second pathway for degradation of PA leading through benzoic acid.Entities:
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Year: 1993 PMID： 8098688 DOI： 10.1016/0742-8413(93)90045-m
Source DB: PubMed Journal: Comp Biochem Physiol C ISSN： 0742-8413