K H Tennekoon1, E H Karunanayake. 1. Department of Physiology, Faculty of Medicine, University of Colombo, Sri Lanka.
Abstract
OBJECTIVE: Delineation of change in male hormone and gonadotropin levels from age 21 to 85. SUBJECTS: Healthy married volunteers with one or more children. METHODS: A 5-mL venous blood sample, serum separated within one hour; testosterone measured by direct RIA, FSH and LH by immunoradiometric assay and magnetic separation. RESULTS: FSH significantly higher from 6th decade, LH from 7th decade; testosterone lower from 6th decade. CONCLUSIONS: Apparently, a rise in FSH and reduction in testosterone precede a rise in LH concentration.
OBJECTIVE: Delineation of change in male hormone and gonadotropin levels from age 21 to 85. SUBJECTS: Healthy married volunteers with one or more children. METHODS: A 5-mL venous blood sample, serum separated within one hour; testosterone measured by direct RIA, FSH and LH by immunoradiometric assay and magnetic separation. RESULTS: FSH significantly higher from 6th decade, LH from 7th decade; testosterone lower from 6th decade. CONCLUSIONS: Apparently, a rise in FSH and reduction in testosterone precede a rise in LH concentration.
Authors: Thomas G Travison; Hubert W Vesper; Eric Orwoll; Frederick Wu; Jean Marc Kaufman; Ying Wang; Bruno Lapauw; Tom Fiers; Alvin M Matsumoto; Shalender Bhasin Journal: J Clin Endocrinol Metab Date: 2017-04-01 Impact factor: 5.958
Authors: L Antonio; D Vanderschueren; N Narinx; K David; J Walravens; P Vermeersch; F Claessens; T Fiers; B Lapauw Journal: Cell Mol Life Sci Date: 2022-10-07 Impact factor: 9.207