Literature DB >> 8096496

Characterization of genetic markers in the 5'flanking region of the apo A1 gene.

C C Shoulders1, T M Narcisi, A Jarmuz, D J Brett, J D Bayliss, J Scott.   

Abstract

Genetic variation of apo A1/C3/A4 is associated with hyperlipidaemia and coronary heart disease. We report the polymerase chain reaction (PCR) conditions for determining three polymorphic sites in the 5'flanking region of apoA1 using DNA prepared from small aliquots of whole blood. These polymorphisms identify six haplotypes that will be of value in genetic studies.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8096496     DOI： 10.1007/bf00222727

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  6 in total

1.  Deletion polymorphism 5' to the human apolipoprotein AI (apo AI) gene.

Authors:  P M Frossard; R T Coleman; A A Protter; J J Seilhamer; H Funke; G Assmann
Journal:  Nucleic Acids Res       Date:  1986-11-11       Impact factor: 16.971

2.  Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase.

Authors:  R K Saiki; D H Gelfand; S Stoffel; S J Scharf; R Higuchi; G T Horn; K B Mullis; H A Erlich
Journal:  Science       Date:  1988-01-29       Impact factor: 47.728

3.  Diagnosis of sickle cell anemia and beta-thalassemia with enzymatically amplified DNA and nonradioactive allele-specific oligonucleotide probes.

Authors:  R K Saiki; C A Chang; C H Levenson; T C Warren; C D Boehm; H H Kazazian; H A Erlich
Journal:  N Engl J Med       Date:  1988-09-01       Impact factor: 91.245

4.  DNA polymorphism haplotypes of the human apolipoprotein APOA1-APOC3-APOA4 gene cluster.

Authors:  S E Antonarakis; P Oettgen; A Chakravarti; S L Halloran; R R Hudson; L Feisee; S K Karathanasis
Journal:  Hum Genet       Date:  1988-11       Impact factor: 4.132

5.  Rapid screening for specific mutations in patients with a clinical diagnosis of familial hypercholesterolaemia.

Authors:  P Talmud; A Tybjaerg-Hansen; D Bhatnagar; A Mbewu; J P Miller; P Durrington; S Humphries
Journal:  Atherosclerosis       Date:  1991-08       Impact factor: 5.162

6.  Tissue-specific expression of apolipoprotein A-I (ApoA-I) is regulated by the 5'-flanking region of the human ApoA-I gene.

Authors:  K Higuchi; S W Law; J M Hoeg; U K Schumacher; N Meglin; H B Brewer
Journal:  J Biol Chem       Date:  1988-12-05       Impact factor: 5.157
  6 in total
  2 in total

1.  Haplotype analysis of the apolipoprotein gene cluster on human chromosome 11.

Authors:  Michael Olivier; Xujing Wang; Regina Cole; Brian Gau; Jessica Kim; Edward M Rubin; Len A Pennacchio
Journal:  Genomics       Date:  2004-05       Impact factor: 5.736

2.  Contribution of polymorphisms in the apolipoprotein AI-CIII-AIV cluster to hyperlipidaemia in patients with gout.

Authors:  F Cardona; F J Tinahones; E Collantes; A Escudero; E García-Fuentes; F J Soriguer
Journal:  Ann Rheum Dis       Date:  2004-04-28       Impact factor: 19.103
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.