Literature DB >> 8096268

Insulin prophylaxis in individuals at high risk of type I diabetes.

R J Keller1, G S Eisenbarth, R A Jackson.   

Abstract

Prevention of type I diabetes is now a practical goal thanks to the ability to define confidently a high-risk group and the success of preventive strategies in animal models. We describe here a pilot trial of low-dose insulin to prevent diabetes in relatives of patients with type I diabetes.

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Year:  1993        PMID: 8096268     DOI: 10.1016/0140-6736(93)91215-8

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  50 in total

Review 1.  Immunotherapy of immune-mediated diabetes. Present and future.

Authors:  N Maclaren
Journal:  Clin Rev Allergy Immunol       Date:  2000-12       Impact factor: 8.667

Review 2.  Immune mechanisms that regulate susceptibility to autoimmune type I diabetes.

Authors:  B Singh; T L Delovitch
Journal:  Clin Rev Allergy Immunol       Date:  2000-12       Impact factor: 8.667

Review 3.  Molecular mimicry in autoimmune disease.

Authors:  S Leech
Journal:  Arch Dis Child       Date:  1998-11       Impact factor: 3.791

4.  Immunomodulatory therapy of human type 1 diabetes: lessons from the mouse.

Authors:  J P Palmer
Journal:  J Clin Invest       Date:  2001-07       Impact factor: 14.808

5.  T-cell response to proinsulin and insulin in type 1 and pretype 1 diabetes.

Authors:  D Dubois-LaForgue; J C Carel; P F Bougnères; J G Guillet; C Boitard
Journal:  J Clin Immunol       Date:  1999-03       Impact factor: 8.317

Review 6.  Latent autoimmune diabetes in adults (LADA).

Authors:  Ramachandra G Naik; Jerry P Palmer
Journal:  Rev Endocr Metab Disord       Date:  2003-09       Impact factor: 6.514

Review 7.  Overview of prevention and intervention trials for type 1 diabetes.

Authors:  Jorge Daaboul; Desmond Schatz
Journal:  Rev Endocr Metab Disord       Date:  2003-12       Impact factor: 6.514

8.  The Effect of DPT-1 Intravenous Insulin Infusion and Daily Subcutaneous Insulin on Endogenous Insulin Secretion and Postprandial Glucose Tolerance.

Authors:  Wei Hao; Carla J Greenbaum; Jeffrey P Krischer; David Cuthbertson; Jennifer B Marks; Jerry P Palmer
Journal:  Diabetes Care       Date:  2015-02-26       Impact factor: 19.112

Review 9.  Novel diagnostic and therapeutic approaches for autoimmune diabetes--a prime time to treat insulitis as a disease.

Authors:  Juha Grönholm; Michael J Lenardo
Journal:  Clin Immunol       Date:  2014-12-05       Impact factor: 3.969

Review 10.  Trials in type 1 diabetes: Antigen-specific therapies.

Authors:  Ken T Coppieters; Leonard C Harrison; Matthias G von Herrath
Journal:  Clin Immunol       Date:  2013-02-15       Impact factor: 3.969

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