| Literature DB >> 8095531 |
Abstract
The incorporation of testosterone and two of its esters, and progesterone and one of its esters (log Poct varying from 3.3 to 6.9) into 2% w/w soybean oil/Brij 96 microemulsions and Brij 96 surfactant systems has been examined. Possible sites of incorporation have been investigated. The drug carrying improvement of an oil-in-water microemulsion over a micellar system appears to depend on the solubility of the drug in the dispersed oil phase and is significant only for very lipophilic drugs.Entities:
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Year: 1993 PMID： 8095531 DOI： 10.1111/j.2042-7158.1993.tb03700.x
Source DB: PubMed Journal: J Pharm Pharmacol ISSN： 0022-3573 Impact factor: 3.765