Literature DB >> 8095027

Marine antitumor agents: 14-deoxycrassin and pseudoplexaurol, new cembranoid diterpenes from the Caribbean gorgonian Pseudoplexaura porosa.

A D Rodríguez1, N Martínez.   

Abstract

Two new cytotoxic antitumor diterpenoids of the cembrane class, named 14-deoxycrassin (3) and pseudoplexaurol (4), have been isolated from the Caribbean gorgonian octocoral Pseudoplexaura porosa. The structure of lactone 3, possessing the infrequently encountered alpha-methylene-delta-lactone ring, has been established from spectral and chemical data and that of alcohol 4 has been established from spectral data.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8095027     DOI： 10.1007/bf01989427

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  4 in total

1.  Chemistry of coelenterates. I. Occurrence of terpenoid compounds in gorgonians.

Authors:  L S CIERESZKO; D H SIFFORD; A J WEINHEIMER
Journal:  Ann N Y Acad Sci       Date:  1960-11-17       Impact factor: 5.691

Review 2.  Marine natural products.

Authors:  D J Faulkner
Journal:  Nat Prod Rep       Date:  1991-04       Impact factor: 13.423

3.  Crassin acetate, the principal antineoplastic agent in four gorgonians of the Pseudoplexaura genus.

Authors:  A J Weinheimer; J A Matson
Journal:  Lloydia       Date:  1975 Sep-Oct

4.  Antineoplastic components of marine animals.

Authors:  G R Pettit; J F Day; J L Hartwell; H B Wood
Journal:  Nature       Date:  1970-08-29       Impact factor: 49.962
  4 in total
  9 in total

Review 1.  Marine antitumor drugs: status, shortfalls and strategies.

Authors:  Ira Bhatnagar; Se-Kwon Kim
Journal:  Mar Drugs       Date:  2010-10-15       Impact factor: 5.118

2.  A cembranoid from tobacco prevents the expression of nicotine-induced withdrawal behavior in planarian worms.

Authors:  Oné R Pagán; Amanda L Rowlands; Angela L Fattore; Tamara Coudron; Kimberly R Urban; Apurva H Bidja; Vesna A Eterović
Journal:  Eur J Pharmacol       Date:  2009-05-30       Impact factor: 4.432

3.  Identification of crassin acetate as a new immunosuppressant triggering heme oxygenase-1 expression in dendritic cells.

Authors:  Hironori Matsushima; Hiroaki Tanaka; Norikatsu Mizumoto; Akira Takashima
Journal:  Blood       Date:  2009-04-28       Impact factor: 22.113

4.  Lobocrassins A-E: new cembrane-type diterpenoids from the soft coral Lobophytum crassum.

Authors:  Chia-Ying Kao; Jui-Hsin Su; Mei-Chin Lu; Tsong-Long Hwang; Wei-Hsien Wang; Jih-Jung Chen; Jyh-Horng Sheu; Yueh-Hsiung Kuo; Ching-Feng Weng; Lee-Shing Fang; Zhi-Hong Wen; Ping-Jyun Sung
Journal:  Mar Drugs       Date:  2011-08-05       Impact factor: 6.085

5.  Draft Genome Sequence of Novosphingobium sp. Strain HII-3, a Bacterium Capable of Degrading the Cembranoid α(β)-2,7,11-Cembratriene-4,6-Diol to Farnesal.

Authors:  Shen Huang; Yumei Qian; Tao Wei; Chunxiao Jia; Pengfei Yang; Duobin Mao
Journal:  Genome Announc       Date:  2018-04-26

6.  Cembranoid-Related Metabolites and Biological Activities from the Soft Coral Sinularia flexibilis.

Authors:  Chia-Hua Wu; Chih-Hua Chao; Tzu-Zin Huang; Chiung-Yao Huang; Tsong-Long Hwang; Chang-Feng Dai; Jyh-Horng Sheu
Journal:  Mar Drugs       Date:  2018-08-09       Impact factor: 5.118

Review 7.  The natural products chemistry of West Indian gorgonian octocorals.

Authors:  Abimael D Rodríguez
Journal:  Tetrahedron       Date:  2001-02-01       Impact factor: 2.457

8.  New cembrane diterpenoids from a Hainan soft coral Sinularia sp.

Authors:  Bin Yang; Xuefeng Zhou; Hui Huang; Xian-Wen Yang; Juan Liu; Xiuping Lin; Xiubao Li; Yan Peng; Yonghong Liu
Journal:  Mar Drugs       Date:  2012-09-18       Impact factor: 6.085

9.  Cell survival and apoptosis signaling as therapeutic target for cancer: marine bioactive compounds.

Authors:  Senthilkumar Kalimuthu; Kim Se-Kwon
Journal:  Int J Mol Sci       Date:  2013-01-24       Impact factor: 5.923
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.