| Literature DB >> 8093748 |
A Chauhan1, S Jameel, J B Dilawari, Y K Chawla, U Kaur, N K Ganguly.
Abstract
Hepatitis E virus (HEV) causes an enteric non-A, non-B hepatitis. The disease occurs in epidemic settings and sporadically, and viral transmission is thought to be faecal-oral. We present here a single volunteer study of HEV transmission followed by disease. Clinical and biochemical features of the infection correlated with HEV detection in the stools and sera by reverse transcription/polymerase chain amplification. IgG antibody has persisted for 2 years. The presence of HEV in serum before clinical signs appeared suggests that in endemic areas sporadic transmission of HEV may also occur parenterally.Entities:
Mesh:
Year: 1993 PMID: 8093748 DOI: 10.1016/0140-6736(93)90008-5
Source DB: PubMed Journal: Lancet ISSN: 0140-6736 Impact factor: 79.321