Literature DB >> 8091680

Nonhomologous recombination between the hemagglutinin gene and the nucleoprotein gene of an influenza virus.

M Orlich1, H Gottwald, R Rott.   

Abstract

Mutants of the influenza virus A/seal/Mass/1/80 (H7N7) are described which contain an insertion of 60 nucleotides in the hemagglutinin (HA) gene, derived most probably by recombination between the HA gene and the nucleoprotein gene of the same virus. The nonhomologous RNA recombination resulted in an enhanced hemagglutinin cleavability associated with broadening of the host cell spectrum, increased hemolytic activity, and increased pathogenicity for chickens.

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Year:  1994        PMID： 8091680     DOI： 10.1006/viro.1994.1555

Source DB:  PubMed          Journal:  Virology        ISSN： 0042-6822            Impact factor:   3.616


  35 in total

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Journal:  Bioinformatics       Date:  2010-04-16       Impact factor: 6.937

2.  A novel eight amino acid insertion contributes to the hemagglutinin cleavability and the virulence of a highly pathogenic avian influenza A (H7N3) virus in mice.

Authors:  Xiangjie Sun; Jessica A Belser; Terrence M Tumpey
Journal:  Virology       Date:  2015-11-26       Impact factor: 3.616

3.  An exact nonparametric method for inferring mosaic structure in sequence triplets.

Authors:  Maciej F Boni; David Posada; Marcus W Feldman
Journal:  Genetics       Date:  2007-04-03       Impact factor: 4.562

4.  Homologous recombination is very rare or absent in human influenza A virus.

Authors:  Maciej F Boni; Yang Zhou; Jeffery K Taubenberger; Edward C Holmes
Journal:  J Virol       Date:  2008-03-19       Impact factor: 5.103

5.  Transfection-mediated generation of functionally competent Tula hantavirus with recombinant S RNA segment.

Authors:  Alexander Plyusnin; Sami K J Kukkonen; Angelina Plyusnina; Olli Vapalahti; Antti Vaheri
Journal:  EMBO J       Date:  2002-03-15       Impact factor: 11.598

6.  Bioinformatic analysis of the genome of infectious salmon anemia virus associated with outbreaks with high mortality in Chile.

Authors:  L Cottet; M Cortez-San Martin; M Tello; E Olivares; A Rivas-Aravena; E Vallejos; A M Sandino; E Spencer
Journal:  J Virol       Date:  2010-09-01       Impact factor: 5.103

7.  Guidelines for identifying homologous recombination events in influenza A virus.

Authors:  Maciej F Boni; Menno D de Jong; H Rogier van Doorn; Edward C Holmes
Journal:  PLoS One       Date:  2010-05-03       Impact factor: 3.240

8.  Pathogenesis, transmissibility, and ocular tropism of a highly pathogenic avian influenza A (H7N3) virus associated with human conjunctivitis.

Authors:  Jessica A Belser; C Todd Davis; Amanda Balish; Lindsay E Edwards; Hui Zeng; Taronna R Maines; Kortney M Gustin; Irma López Martínez; Rodrigo Fasce; Nancy J Cox; Jacqueline M Katz; Terrence M Tumpey
Journal:  J Virol       Date:  2013-03-13       Impact factor: 5.103

9.  Recombination in Tula hantavirus evolution: analysis of genetic lineages from Slovakia.

Authors:  C Sibold; H Meisel; D H Krüger; M Labuda; J Lysy; O Kozuch; M Pejcoch; A Vaheri; A Plyusnin
Journal:  J Virol       Date:  1999-01       Impact factor: 5.103

10.  Infectious salmon anaemia virus (ISAV) isolated from the ISA disease outbreaks in Chile diverged from ISAV isolates from Norway around 1996 and was disseminated around 2005, based on surface glycoprotein gene sequences.

Authors:  Frederick S B Kibenge; Marcos G Godoy; Yingwei Wang; Molly J T Kibenge; Valentina Gherardelli; Soledad Mansilla; Angelica Lisperger; Miguel Jarpa; Geraldine Larroquete; Fernando Avendaño; Marcela Lara; Alicia Gallardo
Journal:  Virol J       Date:  2009-06-26       Impact factor: 4.099
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