Literature DB >> 8090484

Segmental bone deficiency after acute trauma. The role of bone transport.

L J Prokuski1, J L Marsh.   

Abstract

Bone transport, along with allied techniques of compression distraction, offer exciting new treatment alternatives for the difficult problem of segmental bone loss from acute trauma. Many factors must be considered before indicating these treatment methods, because it is clear that many of the problems that existed with more conventional methods also exist with these techniques. The indications for amputation vs. limb salvage must always be considered in these severe injuries. In less severe injuries with minimal bone loss and soft-tissue injury exposing well-vascularized segments of bone, traditional methods of stabilization, soft-tissue coverage, and grafting lead to more rapid healing times and return to function for patients. These techniques are reserved for the most severe type of injuries for which treatment times are long and complications not infrequent. Therefore, methods to speed treatment, avoid complications, and increase patient acceptance should be actively sought. The great advantage of these techniques is that the vast majority of the reconstruction is done on the injured limb segment, with minimal need for extensive donor-site defects.

Entities:  

Mesh:

Year:  1994        PMID: 8090484

Source DB:  PubMed          Journal:  Orthop Clin North Am        ISSN: 0030-5898            Impact factor:   2.472


  6 in total

1.  [Ex-vivo gene therapy with BMP-4 for critically sized defects and enhancement of fracture healing in an osteoporotic animal model].

Authors:  T Rose; H Peng; A Usas; C Josten; F H Fu; J Huard
Journal:  Unfallchirurg       Date:  2005-01       Impact factor: 1.000

2.  The role of cell type in bone healing mediated by ex vivo gene therapy.

Authors:  Tim Rose; Hairong Peng; Hsain-Chung Shen; Arvydas Usas; Ryosuke Kuroda; Helmut Lill; Freddie H Fu; Johnny Huard
Journal:  Langenbecks Arch Surg       Date:  2003-10-08       Impact factor: 3.445

3.  Effect of alpha-tocopherol on bone formation during distraction osteogenesis: a rabbit model.

Authors:  Mustafa Kurklu; Cemil Yildiz; Ozkan Kose; Yuksel Yurttas; Ozgur Karacalioglu; Muhittin Serdar; Salih Deveci
Journal:  J Orthop Traumatol       Date:  2011-07-15

4.  Surgical membranes as directional delivery devices to generate tissue: testing in an ovine critical sized defect model.

Authors:  Melissa L Knothe Tate; Hana Chang; Shannon R Moore; Ulf R Knothe
Journal:  PLoS One       Date:  2011-12-12       Impact factor: 3.240

5.  Management of Osteomyelitis-Induced Massive Tibial Bone Defect by Monolateral External Fixator Combined with Antibiotics-Impregnated Calcium Sulphate: A Retrospective Study.

Authors:  Chenghe Qin; Lei Xu; Juan Liao; Jia Fang; Yanjun Hu
Journal:  Biomed Res Int       Date:  2018-12-19       Impact factor: 3.411

6.  Osteoinduction by combining bone morphogenetic protein (BMP)-2 with a bioactive novel nanocomposite.

Authors:  A Sharma; F Meyer; M Hyvonen; S M Best; R E Cameron; N Rushton
Journal:  Bone Joint Res       Date:  2012-07-01       Impact factor: 5.853

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.