| Literature DB >> 8089591 |
A Thomas1.
Abstract
A Markovian scheme for simulating the genotypes of individuals in a pedigree subject to constraints imposed by observed phenotypes is used to estimate the logarithm of a likelihood ratio in linkage analysis. The method is illustrated on a fictitious pedigree by comparison with exactly calculated results.Mesh：
Year: 1994 PMID： 8089591 DOI： 10.1093/imammb/11.2.79
Source DB: PubMed Journal: IMA J Math Appl Med Biol ISSN： 0265-0746