Literature DB >> 8088833

Assignment of 112 microsatellite markers to 23 chromosome 11 subregions delineated by somatic hybrids: comparison with the genetic map.

P Couillin1, E Le Guern, A Vignal, C Fizames, N Ravisé, D Delportes, I Reguigne, M F Rosier, C Junien, V van Heyningen.   

Abstract

Using a panel of 25 somatic cell hybrids, we have regionally localized 112 microsatellite markers generated by Généthon and assigned to chromosome 11. A genetic map of 74 of them was produced using linkage analysis of the eight largest CEPH (Centre d'Etude du Polymorphisme Humain) families. They could be ordered on chromosome 11 with an average distance of 2.1 cM. The tight correlation observed between the genetic order and the physical assignment of these microsatellites reinforces the genetic map data. These newly localized markers identified by the PCR method using a standardized protocol represent useful tools for mapping YAC clones and establishing YAC contigs and for studying genetic diseases or cancers associated with specific genes and/or germinal/somatic rearrangements of chromosome 11.

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Year:  1994        PMID： 8088833     DOI： 10.1006/geno.1994.1280

Source DB:  PubMed          Journal:  Genomics        ISSN： 0888-7543            Impact factor:   5.736


  7 in total

1.  Primed in situ (PRINS) labelling with Alu and satellite primers for rapid characterization of human chromosomes in hybrid cell lines.

Authors:  P Coullin; B Andréo; J P Charlieu; J J Candelier; F Pellestor
Journal:  Chromosome Res       Date:  1997-08       Impact factor: 5.239

2.  High-resolution meiotic and physical mapping of the best vitelliform macular dystrophy (VMD2) locus to pericentromeric chromosome 11.

Authors:  B H Weber; G Vogt; H Stöhr; S Sander; D Walker; C Jones
Journal:  Am J Hum Genet       Date:  1994-12       Impact factor: 11.025

3.  Epigenetic modification and uniparental inheritance of H19 in Beckwith-Wiedemann syndrome.

Authors:  D Catchpoole; W W Lam; D Valler; I K Temple; J A Joyce; W Reik; P N Schofield; E R Maher
Journal:  J Med Genet       Date:  1997-05       Impact factor: 6.318

4.  Homozygosity by descent for a rare mutation in the myophosphorylase gene is associated with variable phenotypes in a Druze family with McArdle disease.

Authors:  S Iyengar; H Kalinsky; S Weiss; M Korostishevsky; M Sadeh; Y Zhao; K K Kidd; B Bonne-Tamir
Journal:  J Med Genet       Date:  1997-05       Impact factor: 6.318

5.  Congenital fibrosis of the extraocular muscles type 2, an inherited exotropic strabismus fixus, maps to distal 11q13.

Authors:  S M Wang; J Zwaan; P B Mullaney; M H Jabak; A Al-Awad; A H Beggs; E C Engle
Journal:  Am J Hum Genet       Date:  1998-08       Impact factor: 11.025

6.  Refinement of the multiple exostoses locus (EXT2) to a 3-cM interval on chromosome 11.

Authors:  W Wuyts; S Ramlakhan; W Van Hul; J T Hecht; A M van den Ouweland; W H Raskind; F C Hofstede; E Reyniers; D E Wells; B de Vries
Journal:  Am J Hum Genet       Date:  1995-08       Impact factor: 11.025

7.  Chromosome 11 allele imbalance and clinicopathological correlates in ovarian tumours.

Authors:  H Gabra; L Taylor; B B Cohen; A Lessels; D M Eccles; R C Leonard; J F Smyth; C M Steel
Journal:  Br J Cancer       Date:  1995-08       Impact factor: 7.640
  7 in total

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