Literature DB >> 808860

Trimethoprim-sulfamethoxazole in the treatment of gonorrhea: comparison with standard treatment schedules.

W C Duncan, J M Knox, T H Jackson.   

Abstract

Several treatment regimens of trimethoprim-sulfamethoxazole (TMP-SMZ) were compared to the USPHS-recommended schedules for treatment of uncomplicated gonorrhea with ampicillin plus probenecid, tetracycline, or aqueous procaine penicillin G in both men and women. TMP-SMZ, six tablets as a single oral dose daily for 3 days, was as effective as the ampicillin or tetracycline schedules. The drug was well tolerated.

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Year:  1975        PMID： 808860     DOI： 10.1097/00007611-197509000-00020

Source DB:  PubMed          Journal:  South Med J        ISSN： 0038-4348            Impact factor:   0.954


  4 in total

1.  Pharmacokinetics and tolerance of a single twelve-tablet dose of trimethoprim (960 mg)-sulfamethoxazole (4,800 mg).

Authors:  R J Fass; R B Prior; R L Perkins
Journal:  Antimicrob Agents Chemother       Date:  1977-07       Impact factor: 5.191

2.  Sexually transmitted disease.

Authors:  H A Poindexter
Journal:  J Natl Med Assoc       Date:  1977-08       Impact factor: 1.798

Review 3.  Co-trimoxazole (trimethoprim-sulfamethoxazole): an updated review of its antibacterial activity and clinical efficacy.

Authors:  G P Wormser; G T Keusch; R C Heel
Journal:  Drugs       Date:  1982-12       Impact factor: 9.546

4.  Sulfamethoxazole-trimethoprim synergism for Neisseria gonorrhoeae.

Authors:  M F Rein; W C Elliott; J M Swenson; C Thornsberry
Journal:  Antimicrob Agents Chemother       Date:  1980-02       Impact factor: 5.191
  4 in total

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