Literature DB >> 8087473

[Morphofunctional characteristics of the ovaries, thyroid gland and adrenal glands in experimental lead acetate poisoning].

T A Vylegzhanina, T E Kuznetsova, O A Maneeva, I I Novikov, E L Ryzhkovskaia.   

Abstract

Daily doses of 50 mg/kg of lead acetate injected into the laboratory animals induce morphologic changes in the parenchyma of ovaries, thyroid gland, adrenals and compromises neural mediating processes in paraventricular and supraoptic nuclei of hypothalamus. The observed morphologic changes are similar to those characteristic for intensive functioning. Prolonged exposure to lead acetate (daily dose 10 mg/kg) results in adaptation and compensation, which preserves the functional potential of the organs. The morphologic changes in the endocrine organs do not lead to significant hormonal changes.

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Year:  1993        PMID: 8087473

Source DB:  PubMed          Journal:  Med Tr Prom Ekol        ISSN: 1026-9428


  2 in total

1.  Protective role of ascorbic acid on lead-induced damage to the thyroid gland in the rat.

Authors:  Denisse Calderón-Vallejo; María Del Carmen Díaz-Galindo; Andrés Quintanar-Stephano; Carlos Olvera-Sandoval; J Luis Quintanar
Journal:  Toxicol Res (Camb)       Date:  2020-09-16       Impact factor: 3.524

Review 2.  The effect of lead intoxication on endocrine functions.

Authors:  K K Doumouchtsis; S K Doumouchtsis; E K Doumouchtsis; D N Perrea
Journal:  J Endocrinol Invest       Date:  2009-02       Impact factor: 4.256

  2 in total

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