| Literature DB >> 8086510 |
T Fest1, B de Wazières, B Lamy, M Maskani, D Vuitton, J L Dupond.
Abstract
We describe the beneficial effect of recombinant alpha 2b interferon in a woman with an idiopathic and refractory IgM-mediated autoimmune hemolytic anemia due to low-titer, high-thermal-amplitude cold agglutinins. The response was partial but sustained, 2 months after interruption of interferon, with hemoglobin concentrations ranging between 8.5 and 10 g/dl. In the literature, such rarely encountered hemolyzing warm-reacting agglutinins are described as causing severe hemolysis with a frequently fatal clinical outcome.Entities:
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Year: 1994 PMID： 8086510 DOI： 10.1007/bf01695696
Source DB: PubMed Journal: Ann Hematol ISSN： 0939-5555 Impact factor: 3.673