Literature DB >> 8086313

Clearance of LDH-5 from the circulation of inbred mice correlates with binding to macrophages.

T Hayashi1, A L Notkins.   

Abstract

Flow cytometry showed that the enzyme lactate dehydrogenase (LDH-5) binds to peritoneal macrophages. The degree of binding appears to be genetically controlled and varies depending on the inbred strain of mouse. The rate at which LDH-5 is cleared from the circulation correlates with the degree of binding to macrophages. These findings suggest that the binding of LDH-5 to macrophages may serve as an in-vitro index of enzyme clearance.

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Year:  1994        PMID： 8086313      PMCID： PMC2001804     

Source DB:  PubMed          Journal:  Int J Exp Pathol        ISSN： 0959-9673            Impact factor:   1.925


  9 in total

1.  IMPAIRED CLEARANCE OF ENZYMES IN MICE INFECTED WITH THE LACTIC DEHYDROGENASE AGENT.

Authors:  A L NOTKINS; C SCHEELE
Journal:  J Natl Cancer Inst       Date:  1964-10       Impact factor: 13.506

Review 2.  LACTIC DEHYDROGENASE VIRUS.

Authors:  A L NOTKINS
Journal:  Bacteriol Rev       Date:  1965-06

3.  Receptor-mediated endocytosis of lactate dehydrogenase M4 by liver macrophages: a mechanism for elimination of enzymes from plasma. Evidence for competition by creatine kinase MM, adenylate kinase, malate, and alcohol dehydrogenase.

Authors:  M J Smit; A M Duursma; J M Bouma; M Gruber
Journal:  J Biol Chem       Date:  1987-09-25       Impact factor: 5.157

4.  Enhanced clearance of lactic dehydrogenase-5 in severe combined immunodeficiency (SCID) mice: effect of lactic dehydrogenase virus on enzyme clearance.

Authors:  T Hayashi; M Ozaki; I Mori; M Saito; T Itoh; H Yamamoto
Journal:  Int J Exp Pathol       Date:  1992-04       Impact factor: 1.925

5.  Enzymatic and immunologic alterations in mice infected with lactic dehydrogenase virus.

Authors:  A L Notkins
Journal:  Am J Pathol       Date:  1971-09       Impact factor: 4.307

6.  Flow cytometry to identify cell types to which enzymes bind. Effect of lactic dehydrogenase virus on enzyme binding.

Authors:  H Nakayama; T Hayashi; K F Salata; A L Notkins
Journal:  J Biol Chem       Date:  1990-08-25       Impact factor: 5.157

7.  Regulation of enzyme levels in the blood. Influence of environmental and genetic factors on enzyme clearance.

Authors:  T Hayashi; K Salata; A Kingman; A L Notkins
Journal:  Am J Pathol       Date:  1988-09       Impact factor: 4.307

8.  Endocytosis and breakdown of 125I-labelled lactate dehydrogenase isoenzyme M4 by rat liver and spleen in vivo.

Authors:  J Sinke; J M Bouma; T Kooistra; M Gruber
Journal:  Biochem J       Date:  1979-04-15       Impact factor: 3.857

9.  Studies on the mechanism of action of Riley virus. IV. The reticuloendothelial system and impaired plasma enzyme clearance in infected mice.

Authors:  B W Mahy; K E Rowson; C W Parr
Journal:  J Exp Med       Date:  1967-02-01       Impact factor: 14.307
  9 in total
  5 in total

Review 1.  Metabolic Pathway of Cardiospecific Troponins: From Fundamental Aspects to Diagnostic Role (Comprehensive Review).

Authors:  Aleksey M Chaulin
Journal:  Front Mol Biosci       Date:  2022-04-19

2.  The Liver and Kidneys mediate clearance of cardiac troponin in the rat.

Authors:  Aida Muslimovic; Vincent Fridén; Olav Tenstad; Karin Starnberg; Susanne Nyström; Emelie Wesén; Elin K Esbjörner; Kristoffer Granholm; Bertil Lindahl; Ola Hammarsten
Journal:  Sci Rep       Date:  2020-04-22       Impact factor: 4.379

Review 3.  Cardiac Troponins Metabolism: From Biochemical Mechanisms to Clinical Practice (Literature Review).

Authors:  Aleksey M Chaulin
Journal:  Int J Mol Sci       Date:  2021-10-10       Impact factor: 5.923

Review 4.  The Importance of Cardiac Troponin Metabolism in the Laboratory Diagnosis of Myocardial Infarction (Comprehensive Review).

Authors:  Aleksey M Chaulin
Journal:  Biomed Res Int       Date:  2022-03-30       Impact factor: 3.411

Review 5.  Biology of Cardiac Troponins: Emphasis on Metabolism.

Authors:  Aleksey M Chaulin
Journal:  Biology (Basel)       Date:  2022-03-11
  5 in total

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