Literature DB >> 808402

[Treatment of atypical absences with a combination of succinimide and dipropylacetate (author's transl)].

H Schneble.   

Abstract

Fifteen epileptic patients with mild seizures of the narcolepsy type were treated with a combination of succinimide (average dose 750 mg) and dipropylacetate (average dose 1,200 mg), medication with each drug alone having brought no success. The combination of drugs stopped the seizures in eleven patients, in three they almost stopped and in one the frequency of seizures was halved. An E.E.G. was recorded in twelve, with improvement in each. Side effects occurred in five patients (nausea, vomiting, singultus and fatigue), but the drug had to be discontinued in only one instance.

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Year:  1975        PMID: 808402     DOI: 10.1055/s-0028-1106422

Source DB:  PubMed          Journal:  Dtsch Med Wochenschr        ISSN: 0012-0472            Impact factor:   0.628


  2 in total

1.  Treatment of childhood epilepsy with dipropylacetic acid (DPA).

Authors:  I Lagenstein; H J Sternowsky; E Blaschke; M Rothe; R Fehr
Journal:  Arch Psychiatr Nervenkr (1970)       Date:  1978-10-09

Review 2.  Sodium valproate: a review of its pharmacological properties and therapeutic efficacy in epilepsy.

Authors:  R M Pinder; R N Brogden; T M Speight; G S Avery
Journal:  Drugs       Date:  1977-02       Impact factor: 9.546

  2 in total

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