Literature DB >> 8083522

Macrophage mediated tumor cell destruction measured by an alkaline phosphatase assay.

M Modolell1, P G Munder.   

Abstract

A new assay to measure the cytotoxic or growth-inhibitory activity of macrophages against tumor cells is described. The method is based on the fact that, in contrast to macrophages, natural killer cells or cytotoxic lymphocytes, a variety of tumor cells have a very high content of alkaline phosphatase. The strong linearity between tumor cell number and alkaline phosphatase activity in the cultures permits evaluation of macrophage function with standard ELISA equipment.

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Year:  1994        PMID： 8083522     DOI： 10.1016/0022-1759(94)90023-x

Source DB:  PubMed          Journal:  J Immunol Methods        ISSN： 0022-1759            Impact factor:   2.303


  2 in total

1.  Differential pattern of cytokine expression by macrophages infected in vitro with different Mycobacterium tuberculosis genotypes.

Authors:  R Chacón-Salinas; J Serafín-López; R Ramos-Payán; P Méndez-Aragón; R Hernández-Pando; D Van Soolingen; L Flores-Romo; S Estrada-Parra; I Estrada-García
Journal:  Clin Exp Immunol       Date:  2005-06       Impact factor: 4.330

2.  Leishmanicidal and fungicidal activity of lipases obtained from endophytic fungi extracts.

Authors:  Daniela Ribeiro Alves; Selene Maia de Morais; Fernanda Tomiotto-Pellissier; Fábio Roger Vasconcelos; Francisco das Chagas Oliveira Freire; Isaac Neto Goes da Silva; Alan Henrique Depieri Cataneo; Milena Menegazzo Miranda-Sapla; Gustavo Adolfo Saavedra Pinto; Ivete Conchon-Costa; Arlindo de Alencar Araripe Noronha; Wander Rogério Pavanelli
Journal:  PLoS One       Date:  2018-06-18       Impact factor: 3.240
  2 in total

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