PURPOSE: To investigate the potential role of Magnetic Resonance for assessing radiation-Induced lung damage. METHODS AND MATERIALS: T1 and T2 relaxation times were measured for lungs excised from Sprague-Dawley rats at various times following thoracic irradiation. RESULTS: Although on average a 10% increase was observed in the T2 relaxation times between 30 and 80 days after irradiation, this is too small to affect image contrast. CONCLUSIONS: The results indicate that relaxation measurements are unlikely to yield new information to characterize changes in lung tissue caused by radiation.
PURPOSE: To investigate the potential role of Magnetic Resonance for assessing radiation-Induced lung damage. METHODS AND MATERIALS: T1 and T2 relaxation times were measured for lungs excised from Sprague-Dawley rats at various times following thoracic irradiation. RESULTS: Although on average a 10% increase was observed in the T2 relaxation times between 30 and 80 days after irradiation, this is too small to affect image contrast. CONCLUSIONS: The results indicate that relaxation measurements are unlikely to yield new information to characterize changes in lung tissue caused by radiation.
Authors: Maria T A Buzan; Monika Eichinger; Michael Kreuter; Hans-Ulrich Kauczor; Felix J Herth; Arne Warth; Carmen Monica Pop; Claus Peter Heussel; Julien Dinkel Journal: Eur Radiol Date: 2015-06-03 Impact factor: 5.315