| Literature DB >> 8083043 |
F R de Gruijl1, J C Van der Leun.
Abstract
The wavelength dependency of carcinogenesis is an important factor in risk assessments pertaining to sources of ultraviolet radiation, the most important of which is the sun. This wavelength dependency cannot be measured directly in humans, but it has been measured in hairless mice, and represented in an action spectrum. An estimate of the action spectrum for humans can be produced by correcting for differences in epidermal transmission between mice and humans. This carcinogenic action spectrum for humans resembles the action spectrum for ultraviolet-induced erythema (sunburn), and results in small adjustments of earlier estimates of the effects of a stratospheric ozone depletion on skin cancer incidences.Entities:
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Year: 1994 PMID: 8083043 DOI: 10.1097/00004032-199410000-00001
Source DB: PubMed Journal: Health Phys ISSN: 0017-9078 Impact factor: 1.316