Literature DB >> 8082882

The role of sialic acid in the localization of lymphocytes in the spleen.

G Kraal1, K Hoeben, J Brevé, T K van den Berg.   

Abstract

The role of carbohydrate structures in the interaction of lymphocytes and endothelial cells is well established. Here the influence of sialic acid in the entrance and localization of lymphocytes in the lymphoid white pulp area of the spleen was studied by injecting sialidase in vivo. A role for sialic acid molecules on stromal elements of the spleen was determined. Although the identity of the cells that bear sialidase sensitive receptors could not be established, a role for marginal zone macrophages could be ruled out by macrophage depletion studies.

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Year:  1994        PMID: 8082882     DOI: 10.1016/S0171-2985(11)80289-5

Source DB:  PubMed          Journal:  Immunobiology        ISSN: 0171-2985            Impact factor:   3.144


  4 in total

1.  Expression of the mucosal vascular addressin, MAdCAM-1, on sinus-lining cells in the spleen.

Authors:  G Kraal; K Schornagel; P R Streeter; B Holzmann; E C Butcher
Journal:  Am J Pathol       Date:  1995-09       Impact factor: 4.307

2.  NKX2.3 is required for MAdCAM-1 expression and homing of lymphocytes in spleen and mucosa-associated lymphoid tissue.

Authors:  O Pabst; R Förster; M Lipp; H Engel; H H Arnold
Journal:  EMBO J       Date:  2000-05-02       Impact factor: 11.598

Review 3.  Stromal cell contributions to the homeostasis and functionality of the immune system.

Authors:  Scott N Mueller; Ronald N Germain
Journal:  Nat Rev Immunol       Date:  2009-07-31       Impact factor: 53.106

4.  Tolerance and lymphoid organ structure and function.

Authors:  Bryna E Burrell; Yaozhong Ding; Yumi Nakayama; Kyung-Su Park; Jiangnan Xu; Na Yin; Jonathan S Bromberg
Journal:  Front Immunol       Date:  2011-12-07       Impact factor: 7.561

  4 in total

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