Literature DB >> 8082524

The prediction of diabetic neuropathic foot ulceration using vibration perception thresholds. A prospective study.

M J Young1, J L Breddy, A Veves, A J Boulton.   

Abstract

OBJECTIVE: To assess the ability of vibration perception threshold (VPT) to predict the development of diabetic foot ulceration. RESEARCH DESIGN AND METHODS: A prospective follow-up study of consecutive patients with vibration perception measured by biothesiometry from April 1988 to March 1989. Patients were stratified in various risk groups.
RESULTS: Patients with a VPT < 15 V had a cumulative incidence of foot ulceration of 2.9% compared with 19.8% in patients with a VPT > 25 V, odds ratio (OR) 7.99 (3.65-17.5, 95% confidence intervals), P < 0.01. The incidence of ulceration increased with duration of diabetes, but even with this effect removed, the excess of ulceration persisted, OR 6.82 (2.75-16.92), P < 0.01.
CONCLUSIONS: VPT is an effective predictor of the risk of foot ulceration in diabetes and therefore could be used to target foot-care education to those patients most likely to benefit and, thereby, possibly improve its effectiveness.

Entities:  

Mesh:

Year:  1994        PMID: 8082524     DOI: 10.2337/diacare.17.6.557

Source DB:  PubMed          Journal:  Diabetes Care        ISSN: 0149-5992            Impact factor:   19.112


  102 in total

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