Literature DB >> 8082184

Approaching the function of new genes by detection of their potential upstream activation sequences in Saccharomyces cerevisiae: application to chromosome III.

C Fondrat1, A Kalogeropoulos.   

Abstract

The systematic sequencing of the yeast genome reveals the presence of many potential genes of unknown function. One way to approach their function is to define which regulatory system controls their transcription. This can also be accomplished by the detection of an upstream activation sequence (UAS). Such a detection can be done by computer, provided that the definition of a UAS includes sufficient and precise rules. We have established such rules for the UASs of the GAL4, RAP1 (RPG box), GCN4, and the HAP2/HAP3/HAP4 regulatory proteins, as well as for a motif (PAC) frequently found upstream of the genes of the RNA polymerase A and C subunits. These rules were applied to the chromosome III DNA sequence, and gave precise predictions.

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Year:  1994        PMID： 8082184     DOI： 10.1007/bf00351777

Source DB:  PubMed          Journal:  Curr Genet        ISSN： 0172-8083            Impact factor:   3.886


  35 in total

1.  Yeast HAP2 and HAP3 activators both bind to the CYC1 upstream activation site, UAS2, in an interdependent manner.

Authors:  J Olesen; S Hahn; L Guarente
Journal:  Cell       Date:  1987-12-24       Impact factor: 41.582

2.  Nomenclature Committee of the International Union of Biochemistry (NC-IUB). Nomenclature for incompletely specified bases in nucleic acid sequences. Recommendations 1984.

Authors: 
Journal:  Eur J Biochem       Date:  1985-07-01

3.  Consensus patterns in DNA.

Authors:  G D Stormo
Journal:  Methods Enzymol       Date:  1990       Impact factor: 1.600

Review 4.  Control of ribosome biogenesis in yeast.

Authors:  R J Planta; H A Raué
Journal:  Trends Genet       Date:  1988-03       Impact factor: 11.639

5.  Connections between transcriptional activators, silencers, and telomeres as revealed by functional analysis of a yeast DNA-binding protein.

Authors:  A R Buchman; N F Lue; R D Kornberg
Journal:  Mol Cell Biol       Date:  1988-12       Impact factor: 4.272

6.  Improved tools for biological sequence comparison.

Authors:  W R Pearson; D J Lipman
Journal:  Proc Natl Acad Sci U S A       Date:  1988-04       Impact factor: 11.205

7.  Purification and cloning of a DNA binding protein from yeast that binds to both silencer and activator elements.

Authors:  D Shore; K Nasmyth
Journal:  Cell       Date:  1987-12-04       Impact factor: 41.582

8.  Structure and regulation of KGD1, the structural gene for yeast alpha-ketoglutarate dehydrogenase.

Authors:  B Repetto; A Tzagoloff
Journal:  Mol Cell Biol       Date:  1989-06       Impact factor: 4.272

9.  RPC19, the gene for a subunit common to yeast RNA polymerases A (I) and C (III).

Authors:  M Dequard-Chablat; M Riva; C Carles; A Sentenac
Journal:  J Biol Chem       Date:  1991-08-15       Impact factor: 5.157

10.  Comprehensive sequence analysis of the 182 predicted open reading frames of yeast chromosome III.

Authors:  P Bork; C Ouzounis; C Sander; M Scharf; R Schneider; E Sonnhammer
Journal:  Protein Sci       Date:  1992-12       Impact factor: 6.725
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  5 in total

1.  The CCAAT box-binding factor stimulates ammonium assimilation in Saccharomyces cerevisiae, defining a new cross-pathway regulation between nitrogen and carbon metabolisms.

Authors:  V D Dang; C Bohn; M Bolotin-Fukuhara; B Daignan-Fornier
Journal:  J Bacteriol       Date:  1996-04       Impact factor: 3.490

Review 2.  Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.

Authors:  F Galibert; D Alexandraki; A Baur; E Boles; N Chalwatzis; J C Chuat; F Coster; C Cziepluch; M De Haan; H Domdey; P Durand; K D Entian; M Gatius; A Goffeau; L A Grivell; A Hennemann; C J Herbert; K Heumann; F Hilger; C P Hollenberg; M E Huang; C Jacq; J C Jauniaux; C Katsoulou; L Karpfinger-Hartl
Journal:  EMBO J       Date:  1996-05-01       Impact factor: 11.598

3.  Quantitative discrimination of MEF2 sites.

Authors:  J W Fickett
Journal:  Mol Cell Biol       Date:  1996-01       Impact factor: 4.272

4.  Common features and interesting differences in transcriptional responses to secretion stress in the fungi Trichoderma reesei and Saccharomyces cerevisiae.

Authors:  Mikko Arvas; Tiina Pakula; Karin Lanthaler; Markku Saloheimo; Mari Valkonen; Tapani Suortti; Geoff Robson; Merja Penttilä
Journal:  BMC Genomics       Date:  2006-02-22       Impact factor: 3.969

5.  Complete DNA sequence of yeast chromosome II.

Authors:  H Feldmann; M Aigle; G Aljinovic; B André; M C Baclet; C Barthe; A Baur; A M Bécam; N Biteau; E Boles; T Brandt; M Brendel; M Brückner; F Bussereau; C Christiansen; R Contreras; M Crouzet; C Cziepluch; N Démolis; T Delaveau; F Doignon; H Domdey; S Düsterhus; E Dubois; B Dujon; M El Bakkoury; K D Entian; M Feurmann; W Fiers; G M Fobo; C Fritz; H Gassenhuber; N Glandsdorff; A Goffeau; L A Grivell; M de Haan; C Hein; C J Herbert; C P Hollenberg; K Holmstrøm; C Jacq; M Jacquet; J C Jauniaux; J L Jonniaux; T Kallesøe; P Kiesau; L Kirchrath; P Kötter; S Korol; S Liebl; M Logghe; A J Lohan; E J Louis; Z Y Li; M J Maat; L Mallet; G Mannhaupt; F Messenguy; T Miosga; F Molemans; S Müller; F Nasr; B Obermaier; J Perea; A Piérard; E Piravandi; F M Pohl; T M Pohl; S Potier; M Proft; B Purnelle; M Ramezani Rad; M Rieger; M Rose; I Schaaff-Gerstenschläger; B Scherens; C Schwarzlose; J Skala; P P Slonimski; P H Smits; J L Souciet; H Y Steensma; R Stucka; A Urrestarazu; Q J van der Aart; L van Dyck; A Vassarotti; I Vetter; F Vierendeels; S Vissers; G Wagner; P de Wergifosse; K H Wolfe; M Zagulski; F K Zimmermann; H W Mewes; K Kleine
Journal:  EMBO J       Date:  1994-12-15       Impact factor: 11.598
  5 in total

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