M C Chamberlain1. 1. Department of Neurosciences, University of California, San Diego 92103-0812.
Abstract
BACKGROUND: Ten percent of patients with acquired immune deficiency syndrome (AIDS) have intracerebral mass lesions of which the majority are due either to toxoplasmosis or primary central nervous system lymphomas. METHODS: Three patients with AIDS presented with solitary intracerebral mass lesions and were found by pathologic examination to have gliomas. RESULTS: After surgery, all patients were treated with radiotherapy and procarbazine, comustine, and vincristine multiagent chemotherapy. Median follow-up is 12 months. CONCLUSIONS: Occasionally, patients with AIDS and intracerebral mass lesions have primary nonlymphomatous brain tumors, an occurrence not related clearly to underlying immunoincompetence.
BACKGROUND: Ten percent of patients with acquired immune deficiency syndrome (AIDS) have intracerebral mass lesions of which the majority are due either to toxoplasmosis or primary central nervous system lymphomas. METHODS: Three patients with AIDS presented with solitary intracerebral mass lesions and were found by pathologic examination to have gliomas. RESULTS: After surgery, all patients were treated with radiotherapy and procarbazine, comustine, and vincristine multiagent chemotherapy. Median follow-up is 12 months. CONCLUSIONS: Occasionally, patients with AIDS and intracerebral mass lesions have primary nonlymphomatous brain tumors, an occurrence not related clearly to underlying immunoincompetence.