Literature DB >> 8081644

Therapeutic interaction of lamotrigine and sodium valproate in intractable myoclonic epilepsy.

C D Ferrie1, C P Panayiotopoulos.   

Abstract

The clinical and EEG features of a 13-year-old girl with an unusual refractory myoclonic epilepsy is presented. Control was achieved only when lamotrigine was combined with sodium valproate. This may represent a specific pharmacodynamic interaction between these drugs with implications for therapy in the generalized epilepsies.

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Year:  1994        PMID: 8081644     DOI: 10.1016/s1059-1311(05)80208-0

Source DB:  PubMed          Journal:  Seizure        ISSN: 1059-1311            Impact factor:   3.184


  12 in total

Review 1.  The new antiepileptic drugs.

Authors:  R E Appleton
Journal:  Arch Dis Child       Date:  1996-09       Impact factor: 3.791

Review 2.  Pharmacokinetic interactions of the new antiepileptic drugs.

Authors:  B Rambeck; U Specht; P Wolf
Journal:  Clin Pharmacokinet       Date:  1996-10       Impact factor: 6.447

3.  Effects of combined lamotrigine and valproate on basal and stimulated extracellular amino acids and monoamines in the hippocampus of freely moving rats.

Authors:  Shagufta Ahmad; Leslie J Fowler; Peter S Whitton
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2005-01-20       Impact factor: 3.000

Review 4.  Lamotrigine. A review of its use in childhood epilepsy.

Authors:  C R Culy; K L Goa
Journal:  Paediatr Drugs       Date:  2000 Jul-Aug       Impact factor: 3.022

Review 5.  Drug treatment of epilepsy in elderly people: focus on valproic Acid.

Authors:  Linda J Stephen
Journal:  Drugs Aging       Date:  2003       Impact factor: 3.923

6.  Comparison and effects of acute lamotrigine treatment on extracellular excitatory amino acids in the hippocampus of PTZ-kindled epileptic and PTZ-induced status epilepticus rats.

Authors:  Yan Deng; Minghuan Wang; Wei Wang; Chao Ma; Nongyue He
Journal:  Neurochem Res       Date:  2012-12-11       Impact factor: 3.996

7.  Lamotrigine and valproate pharmacokinetics interactions in epileptic patients.

Authors:  Mladena Lalic; Jelena Cvejic; Jovan Popovic; Ksenija Bozic; Svetlana Golocorbin-Kon; Hani Al-Salami; Momir Mikov
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2009 Apr-Jun       Impact factor: 2.441

Review 8.  Lamotrigine. An update of its pharmacology and therapeutic use in epilepsy.

Authors:  A Fitton; K L Goa
Journal:  Drugs       Date:  1995-10       Impact factor: 9.546

Review 9.  Drug interactions with the newer antiepileptic drugs (AEDs)--part 1: pharmacokinetic and pharmacodynamic interactions between AEDs.

Authors:  Philip N Patsalos
Journal:  Clin Pharmacokinet       Date:  2013-11       Impact factor: 6.447

10.  Specific safety and tolerability considerations in the use of anticonvulsant medications in children.

Authors:  Amy Z Crepeau; Brian D Moseley; Elaine C Wirrell
Journal:  Drug Healthc Patient Saf       Date:  2012-06-06
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