Literature DB >> 8076832

Two rat homologs of clathrin-associated adaptor proteins.

J Pevsner1, W Volknandt, B R Wong, R H Scheller.   

Abstract

A cDNA clone predicted to encode a 46,757-Da protein was isolated from a library derived from the electric lobe of the ray Discopyge ommata. Two rat homologs, p47A and p47B, were subsequently isolated. These three proteins share approx. 80% amino acid (aa) identity to each other and have 27-30% aa identity to rat AP50 and mouse AP47, the medium-chain subunits of adaptor complexes associated with clathrin-coated vesicles. These complexes are involved in receptor-mediated pathways of intracellular transport. Rat p47A mRNA is expressed in all tissues examined, including brain, heart, kidney, liver, lung, muscle and spinal cord. Rat p47B mRNA is detected exclusively in brain and spinal cord, and may participate in nervous system-specific functions such as biogenesis or recycling of synaptic vesicles.

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Year:  1994        PMID： 8076832     DOI： 10.1016/0378-1119(94)90306-9

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  25 in total

1.  The AP-3 complex required for endosomal synaptic vesicle biogenesis is associated with a casein kinase Ialpha-like isoform.

Authors:  V V Faundez; R B Kelly
Journal:  Mol Biol Cell       Date:  2000-08       Impact factor: 4.138

2.  Distinct and redundant functions of mu1 medium chains of the AP-1 clathrin-associated protein complex in the nematode Caenorhabditis elegans.

Authors:  J Shim; P W Sternberg; J Lee
Journal:  Mol Biol Cell       Date:  2000-08       Impact factor: 4.138

Review 3.  The molecular characterization of transport vesicles.

Authors:  D G Robinson; G Hinz; S E Holstein
Journal:  Plant Mol Biol       Date:  1998-09       Impact factor: 4.076

4.  Sequence requirements for the recognition of tyrosine-based endocytic signals by clathrin AP-2 complexes.

Authors:  W Boll; H Ohno; Z Songyang; I Rapoport; L C Cantley; J S Bonifacino; T Kirchhausen
Journal:  EMBO J       Date:  1996-11-01       Impact factor: 11.598

5.  Regulatory interactions in the recognition of endocytic sorting signals by AP-2 complexes.

Authors:  I Rapoport; M Miyazaki; W Boll; B Duckworth; L C Cantley; S Shoelson; T Kirchhausen
Journal:  EMBO J       Date:  1997-05-01       Impact factor: 11.598

6.  AP-3: an adaptor-like protein complex with ubiquitous expression.

Authors:  E C Dell'Angelica; H Ohno; C E Ooi; E Rabinovich; K W Roche; J S Bonifacino
Journal:  EMBO J       Date:  1997-03-03       Impact factor: 11.598

7.  Altered expression of a novel adaptin leads to defective pigment granule biogenesis in the Drosophila eye color mutant garnet.

Authors:  C E Ooi; J E Moreira; E C Dell'Angelica; G Poy; D A Wassarman; J S Bonifacino
Journal:  EMBO J       Date:  1997-08-01       Impact factor: 11.598

8.  A neuronal form of the cell adhesion molecule L1 contains a tyrosine-based signal required for sorting to the axonal growth cone.

Authors:  H Kamiguchi; V Lemmon
Journal:  J Neurosci       Date:  1998-05-15       Impact factor: 6.167

9.  Upregulation of μ3A Drives Homeostatic Plasticity by Rerouting AMPAR into the Recycling Endosomal Pathway.

Authors:  Celine C Steinmetz; Vedakumar Tatavarty; Ken Sugino; Yasuyuki Shima; Anne Joseph; Heather Lin; Michael Rutlin; Mary Lambo; Chris M Hempel; Benjamin W Okaty; Suzanne Paradis; Sacha B Nelson; Gina G Turrigiano
Journal:  Cell Rep       Date:  2016-08-25       Impact factor: 9.423

10.  Genomic organization and linkage via a bidirectional promoter of the AP-3 (adaptor protein-3) mu3A and AK (adenosine kinase) genes: deletion mutants of AK in Chinese hamster cells extend into the AP-3 mu3A gene.

Authors:  Bhag Singh; Radhey S Gupta
Journal:  Biochem J       Date:  2004-03-01       Impact factor: 3.857
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