Literature DB >> 807631

Thymus influence on the conversion of 19S to 7S antibody formation in the response to TNP-Brucella.

T J Romano, G J Thorbecke.   

Abstract

Serially transferred LAF spleen cells show a deficient 7S PFC response to TNP-Brucella when Tx as compared to normal irradiated intermediate hosts are used. This defect can be corrected by combining the spleen cells with lymph node cells from the Tx intermediate hosts. It is concluded that T helper cells, residing primarily in lymph node, are needed for efficient 19S leads to 7S conversion in the immune response.

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Year:  1975        PMID: 807631

Source DB:  PubMed          Journal:  J Immunol        ISSN: 0022-1767            Impact factor:   5.422


  3 in total

1.  Age-related humoral antibody responses of AKR/J mice to T-cell dependent and independent antigens.

Authors:  B A Hatten; H Dunton
Journal:  Immunology       Date:  1978-11       Impact factor: 7.397

2.  Role of T cells in the development of memory B cells. Quantitative and qualitative analysis.

Authors:  D E Lafrenz; T L Feldbush
Journal:  Immunology       Date:  1981-09       Impact factor: 7.397

3.  Antigen requirements for priming of IgG producing B memory cells specific for Type III pneumococcal polysaccharide.

Authors:  H Braley-Mullen
Journal:  Immunology       Date:  1980-08       Impact factor: 7.397

  3 in total

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