Literature DB >> 807592

A study of thyroid stimulating activity in human serum with the highly sensitive cytochemical bioassay.

V Petersen, R Hall, B F Smith.   

Abstract

The cytochemical bioassay is able to detect minute amounts of thyroteopin and thyroid stimulating immunoglobulins. Estimations of serum TSH by the cytochemical bioassay are in good agreement with values obtain by radioimmunoassay. In untreated hyperthyroid patients with Graves' disease the TSH levels are significantly lower than in control subjects. Thyroid stimulating immunoglobulins showed a delayed time corse of action in the bioassy and this provided a voncenient method of distinguishing between the two thyroid stimulators.

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Year:  1975        PMID: 807592     DOI: 10.1210/jcem-41-1-199

Source DB:  PubMed          Journal:  J Clin Endocrinol Metab        ISSN: 0021-972X            Impact factor:   5.958


  6 in total

1.  Cytochemical methods of hormone assay.

Authors:  L Bitensky
Journal:  J Clin Pathol Suppl (Assoc Clin Pathol)       Date:  1976

2.  Idiopathic hypopituitarism with biologically inactive TSH.

Authors:  P E Belchetz
Journal:  Proc R Soc Med       Date:  1976-06

3.  Further studies on the response of a cytochemical bioassay to thyroid stimulators, using reference preparations of thyrotropin and long acting thyroid stimulator.

Authors:  P A Ealey; N J Marshall; R P Ekins
Journal:  J Endocrinol Invest       Date:  1984-02       Impact factor: 4.256

Review 4.  Cytochemistry in the bioassay of hormones.

Authors:  J Chayen; L Bitensky
Journal:  J Clin Pathol       Date:  1981-06       Impact factor: 3.411

5.  Clinical application of a cytochemical bioassay for the determination of thyroid stimulating hormone.

Authors:  T Hashimoto; K D Döhler; D Emrich; A von zur Mühlen
Journal:  J Endocrinol Invest       Date:  1979 Oct-Dec       Impact factor: 4.256

6.  Intrinsic bioactivity of thyrotropin in human serum is inversely correlated with thyroid hormone concentrations. Application of a new bioassay using the FRTL-5 rat thyroid cell strain.

Authors:  P A Dahlberg; P A Petrick; M Nissim; M M Menezes-Ferreira; B D Weintraub
Journal:  J Clin Invest       Date:  1987-05       Impact factor: 14.808

  6 in total

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