Literature DB >> 8071905

An experimental model to study the blink reflex.

G S Terrell1, J K Terzis.   

Abstract

A model to study the blink reflex in the experimental setting has been established. The behavioral, electrophysiologic, pathologic, and surgical methods and results obtained parallel those utilized and observed in the human and simulate the problem of facial paralysis. The observation that the blink can be elicited in an animal model, with the same stimuli as in humans, strengthens the value of this model, as do the similarities seen in the electrophysiologic recordings of NCV studies. The dual innervation of the rat eye sphincter allows application of the principle of selectively neurectomizing eye branches and "borrowing" motor-nerve fibers from the normal side, without causing eye-sphincter paralysis, a concept employed extensively in cross-facial nerve-grafting procedures in humans with facial paralysis.

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Year:  1994        PMID: 8071905     DOI: 10.1055/s-2007-1006585

Source DB:  PubMed          Journal:  J Reconstr Microsurg        ISSN: 0743-684X            Impact factor:   2.873


  3 in total

1.  Evidence for facial nerve-independent mechanisms of blinking in the rat.

Authors:  James T Heaton; Jeffrey Kowaleski; Colin Edwards; Christopher Smitson; Tessa A Hadlock
Journal:  Invest Ophthalmol Vis Sci       Date:  2009-08-26       Impact factor: 4.799

Review 2.  Methods for in vivo studies in rodents of chemotherapy induced peripheral neuropathy.

Authors:  Jordi Bruna; Paola Alberti; Aina Calls-Cobos; Martial Caillaud; M Imad Damaj; Xavier Navarro
Journal:  Exp Neurol       Date:  2019-12-15       Impact factor: 5.330

3.  Standardization of techniques used in facial nerve section and facial movement evaluation in rats.

Authors:  Simone Damasceno de Faria; José Ricardo Gurgel Testa; Andrei Borin; Ronaldo N Toledo
Journal:  Braz J Otorhinolaryngol       Date:  2006 May-Jun
  3 in total

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