| Literature DB >> 8069971 |
Y Endo1, H Hayashi, T Sato, M Maruno, T Ohta, S Nozoe.
Abstract
Monoamine oxidase B (MAO-B) inhibitors were isolated from the bark of a Brazilian plant, Himatanthus sucuuba (SPR.). Assignments of the 1H- and 13C-NMR data using two dimensional (2D)-NMR techniques showed the active components to be known lichen depsides, confluentic acid (1) and 2'-O-methylperlatolic acid (2). The depside (1) showed selective inhibition of MAO-B with IC50 value of 0.22 microM.Entities:
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Year: 1994 PMID： 8069971 DOI： 10.1248/cpb.42.1198
Source DB: PubMed Journal: Chem Pharm Bull (Tokyo) ISSN： 0009-2363 Impact factor: 1.645