Literature DB >> 8069687

Evidence that neuropeptide Y is a physiological signal for normal food intake.

M G Dube1, B Xu, W R Crowley, P S Kalra, S P Kalra.   

Abstract

Neuropeptide Y is the most potent orexigenic signal known. To test the hypothesis that NPY is a physiological messenger molecule for normal food intake in rats, we studied the effects of passive immunization against endogenous NPY on cumulative daily food intake in non-fasted spontaneously feeding rats. The results show that continuous central infusion of NPY antibodies markedly suppressed the nighttime and the cumulative 24 h food intake in a dose-dependent fashion. These results support the hypothesis that NPY may be a physiological signal involved in the stimulation of ingestive behavior in rats.

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Year:  1994        PMID： 8069687     DOI： 10.1016/0006-8993(94)90103-1

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  12 in total

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Review 2.  Impact of leucine on energy balance.

Authors:  Liam McAllan; Paul D Cotter; Helen M Roche; Riitta Korpela; Kanishka N Nilaweera
Journal:  J Physiol Biochem       Date:  2012-04-26       Impact factor: 4.158

Review 3.  Neuropeptide Y in normal eating and in genetic and dietary-induced obesity.

Authors:  B Beck
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2006-07-29       Impact factor: 6.237

4.  NPY receptors as potential targets for anti-obesity drug development.

Authors:  Ernie Yulyaningsih; Lei Zhang; Herbert Herzog; Amanda Sainsbury
Journal:  Br J Pharmacol       Date:  2011-07       Impact factor: 8.739

Review 5.  Neuroendocrine actions and regulation of hypothalamic neuropeptide Y during lactation.

Authors:  W R Crowley; G Ramoz; R Torto; K A Keefe; J J Wang; S P Kalra
Journal:  Peptides       Date:  2007-01-22       Impact factor: 3.750

6.  Modulation of neuropeptide Y expression in adult mice does not affect feeding.

Authors:  Linda Ste Marie; Serge Luquet; Toby B Cole; Richard D Palmiter
Journal:  Proc Natl Acad Sci U S A       Date:  2005-12-08       Impact factor: 11.205

7.  Downregulation of fasting-induced cAMP response element-mediated gene induction by leptin in neuropeptide Y neurons of the arcuate nucleus.

Authors:  M Shimizu-Albergine; D L Ippolito; J A Beavo
Journal:  J Neurosci       Date:  2001-02-15       Impact factor: 6.167

8.  Food intake in free-feeding and energy-deprived lean rats is mediated by the neuropeptide Y5 receptor.

Authors:  L Criscione; P Rigollier; C Batzl-Hartmann; H Rüeger; A Stricker-Krongrad; P Wyss; L Brunner; S Whitebread; Y Yamaguchi; C Gerald; R O Heurich; M W Walker; M Chiesi; W Schilling; K G Hofbauer; N Levens
Journal:  J Clin Invest       Date:  1998-12-15       Impact factor: 14.808

Review 9.  Neuropeptide Y: a physiological orexigen modulated by the feedback action of ghrelin and leptin.

Authors:  Satya P Kalra; Pushpa S Kalra
Journal:  Endocrine       Date:  2003-10       Impact factor: 3.633

10.  Dietary isoflavones alter regulatory behaviors, metabolic hormones and neuroendocrine function in Long-Evans male rats.

Authors:  Edwin D Lephart; James P Porter; Trent D Lund; Lihong Bu; Kenneth Dr Setchell; Gina Ramoz; William R Crowley
Journal:  Nutr Metab (Lond)       Date:  2004-12-23       Impact factor: 4.169
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