| Literature DB >> 80688 |
J J Bernier, C Florent, C Desmazures, C Aymes, C L'Hirondel.
Abstract
Alpha1-antitrypsin was assessed, in 10 patients with protein-losing enteropathy and 13 control subjects, as an endogenous marker of plasma-protein loss into the gastrointestinal tract. Both faecal alpha1-A.T. concentrations and faecal alpha1-A.T. clearance were significantly higher in patients than in controls. Wtih clearance there was no overlap between the groups. Over 10 days the normal gastrointestinal clearance of alpha1-A.T. was 3.07 +/- 2.25 (S.D.) ml/day. Measurement of alpha1-A.T. clearance is easy and requires no radioisotopes.Entities:
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Year: 1978 PMID： 80688 DOI： 10.1016/s0140-6736(78)92650-8
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321