Literature DB >> 806662

Relative quantitative assay of the biological activity of interferon messenger ribonucleic acid.

L H Kronenberg, T Friedmann.   

Abstract

RNA extracted from cells previously stimulated to synthesize the antiviral protein, interferon, causes species-specific interferon synthesis when added to heterospecific cell cultures. Our results confirm the report of De Maeyer-Geugnard, De Maeyer & Montagnier (1972). We have used this observation to obtain a relative quantitative assay for the interferon messenger RNA activity. At appropriate RNA concentrations, the yield of interferon is proportional to the concentration of RNA adsorbed to recipient cell cultures.

Mesh：

Substances：

Year:  1975        PMID： 806662     DOI： 10.1099/0022-1317-27-2-225

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  6 in total

1.  Priming activity of mouse interferon: effect on interferon messenger RNA synthesis.

Authors:  S Saito; T Matsuno; T Sudo; E Furuya; S Kohno
Journal:  Arch Virol       Date:  1976       Impact factor: 2.574

2.  Transfer of Fv-1 locus-specific resistance to murine N-tropic and B-tropic retroviruses by cytoplasmic RNA.

Authors:  W K Yang; R W Tennant; R J Rascati; J A Otten; B Schluter; J O Kiggans; F E Myer; A Brown
Journal:  J Virol       Date:  1978-08       Impact factor: 5.103

3.  Biological detection of specific mRNA molecules by microinjection.

Authors:  C P Liu; D L Slate; R Gravel; F H Ruddle
Journal:  Proc Natl Acad Sci U S A       Date:  1979-09       Impact factor: 11.205

4.  Combined antiviral effects of interferon, adenine, arabinoside, hypoxanthine arabinoside, and adenine arabinoside-5'-monophosphate in human fibroblast cultures.

Authors:  Y J Bryson; L H Kronenberg
Journal:  Antimicrob Agents Chemother       Date:  1977-02       Impact factor: 5.191

5.  Synthesis of human interferon by Xenopus laevis oocytes: two structural genes for interferons in human cells.

Authors:  R L Cavalieri; E A Havell; J Vilcek; S Pestka
Journal:  Proc Natl Acad Sci U S A       Date:  1977-08       Impact factor: 11.205

6.  The biological relationship of mouse hepatitis virus (MHV) strains and interferon: in vitro induction and sensitivities.

Authors:  L E Garlinghouse; A L Smith; T Holford
Journal:  Arch Virol       Date:  1984       Impact factor: 2.574
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.