Literature DB >> 8065502

The conversion of ethanolamine and of its metabolites to choline in human neuroblastoma clones: effect of differentiation induced by retinoic acid.

N E Haidar1, C Andriamampandry, M Carrara, J N Kanfer, L Freysz, H Dreyfus, R Massarelli.   

Abstract

The sequential methylation of ethanolamine (Etn) or phosphorylethanolamine to the corresponding choline (Cho) derivatives was studied in both undifferentiated and retinoic acid (RA) differentiated human neuroblastoma clones LA-N-1 and LA-N-2. Conversion of Etn derivatives to the respective Cho metabolites was low in both cell types. However, after treatment of the cultures with ethanol or RA, the methylation of phosphoryl-Etn was stimulated while that of phosphatidyl-Etn was severely reduced in both cholinergic LA-N-2 and catecholaminergic LA-N-1 cells.

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Year:  1994        PMID： 8065502     DOI： 10.1007/bf00967324

Source DB:  PubMed          Journal:  Neurochem Res        ISSN： 0364-3190            Impact factor:   3.996


  26 in total

1.  A rat brain cytosolic N-methyltransferase(s) activity converting phosphorylethanolamine into phosphorylcholine.

Authors:  C Andriamampandry; R Massarelli; L Freysz; J N Kanfer
Journal:  Biochem Biophys Res Commun       Date:  1990-09-14       Impact factor: 3.575

2.  Retinoic acid inhibits phosphatidylinositol turnover only in RA-sensitive while not in RA-resistant human neuroblastoma cells.

Authors:  M Lanciotti; P Longone; P Cornaglia-Ferraris; M Ponzoni
Journal:  Biochem Biophys Res Commun       Date:  1989-05-30       Impact factor: 3.575

3.  Retinoic acid treatment of fibroblasts causes a rapid decrease in [3H]inositol uptake.

Authors:  R Sinha; K E Creek; C Silverman-Jones; L M De Luca
Journal:  Exp Cell Res       Date:  1989-04       Impact factor: 3.905

4.  Alcohols selectively stimulate phospholipase D-mediated hydrolysis of phosphatidylethanolamine in NIH 3T3 cells.

Authors:  Z Kiss; W B Anderson
Journal:  FEBS Lett       Date:  1989-10-23       Impact factor: 4.124

5.  Conversion of ethanolamine, monomethylethanolamine and dimethylethanolamine to choline-containing compounds by neurons in culture and by the rat brain.

Authors:  C Andriamampandry; L Freysz; J N Kanfer; H Dreyfus; R Massarelli
Journal:  Biochem J       Date:  1989-12-01       Impact factor: 3.857

6.  Influence of ethanol on fatty acid composition of phospholipids in cultured neurons.

Authors:  M Morrisson; P A Wilce; B C Shanley
Journal:  Biochem Biophys Res Commun       Date:  1984-07-31       Impact factor: 3.575

Review 7.  Regulation of phosphatidylcholine metabolism in mammalian hearts.

Authors:  G M Hatch; K O; P C Choy
Journal:  Biochem Cell Biol       Date:  1989 Feb-Mar       Impact factor: 3.626

8.  Effects of ethanol on phospholipid acylation in rat erythrocytes: a model for a biochemical approach to membrane adaptation.

Authors:  M Gastaldi; B Lerique; A Vérine; A Valette; J Boyer
Journal:  Drug Alcohol Depend       Date:  1991-10       Impact factor: 4.492

9.  Ethanol is a potent stimulator of phosphatidylcholine breakdown in cultured rat hepatocytes.

Authors:  R A Pittner; J N Fain
Journal:  Biochim Biophys Acta       Date:  1992-02-03

10.  Effects of retinoic acid (RA) on the growth and phenotypic expression of several human neuroblastoma cell lines.

Authors:  N Sidell; A Altman; M R Haussler; R C Seeger
Journal:  Exp Cell Res       Date:  1983-10       Impact factor: 3.905
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  2 in total

1.  Increased levels of methylated intermediates of phosphatidylcholine lead to enhanced phospholipase D activity.

Authors:  T Q Jacobs; B Passarello; J Horwitz
Journal:  Neurochem Res       Date:  1998-08       Impact factor: 3.996

2.  Differential alterations of ethanolamine and choline phosphoglyceride metabolism by clofibrate and retinoic acid in human fibroblasts are not mediated by phorbol ester-sensitive protein kinase C.

Authors:  S G Mandla; D M Byers; N D Ridgway; H W Cook
Journal:  Lipids       Date:  1996-07       Impact factor: 1.880
  2 in total

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