Literature DB >> 806515

The adjuvant activity of a non-toxic, water-soluble glycopeptide present in large quantities in the culture filtrate of Mycobacterium tuberculosis strain DT.

D E Stewart-Tull, T Shimono, S Kotani, M Kato, Y Ogawa, Y Yamamura, T Koga, C M Pearson.   

Abstract

A water-soluble mycobacterial glycopeptide was obtained in large quantities from the culture supernatant fluid of M. tuberculosis strain DT. This glycopeptide was strongly adjuvant-active when injected, in a water-in-oil emulsion contianing ovalbumin, into guinea-pigs. In addition, it was devoid of cord factor toxicity in mice, polyarthritogenic activity in rats and cavity stimulating activity in rabbit lungs.

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Year:  1975        PMID： 806515      PMCID： PMC1445873     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  23 in total

1.  CORRELATION OF ADJUVANT ACTIVITY AND CHEMICAL STRUCTURE OF WAX D FRACTIONS OF MYCOBACTERIA.

Authors:  R G WHITE; P JOLLES; D SAMOUR; E LEDERER
Journal:  Immunology       Date:  1964-03       Impact factor: 7.397

2.  Isolation, identification, and classification of proteins of tuberculin and the tubercle bacillus.

Authors:  F B SEIBERT; E S FIGUEROA; E H DUFOUR
Journal:  Am Rev Tuberc       Date:  1955-05

3.  The pathogenesis of tuberculous cavities.

Authors:  Y YAMAMURA
Journal:  Bibl Tuberc       Date:  1958

4.  A toxic lipid component of the tubercle bacillus (cord factor). III. Occurrence and distribution in various bacterial extracts.

Authors:  J ASSELINEAU; H BLOCH; E LEDERER
Journal:  Am Rev Tuberc       Date:  1953-06

5.  The covalent murein-lipoprotein structure of the Escherichia coli cell wall. The attachment site of the lipoprotein on the murein.

Authors:  V Braun; U Sieglin
Journal:  Eur J Biochem       Date:  1970-04

6.  Chemical characterization, spatial distribution and function of a lipoprotein (murein-lipoprotein) of the E. coli cell wall. The specific effect of trypsin on the membrane structure.

Authors:  V Braun; K Rehn
Journal:  Eur J Biochem       Date:  1969-10

7.  The affinity of mycobacterial glycopetides for guinea-pig gamma immunoglobulin and its fragments.

Authors:  D E Stewart-Tull; P C Wilkinson
Journal:  Immunology       Date:  1973-08       Impact factor: 7.397

8.  The affinity of a mycobacterial glycopeptide for guinea-pig gamma-globulin.

Authors:  D E Stewart-Tull; P C Wilkinson; R G White
Journal:  Immunology       Date:  1965-08       Impact factor: 7.397

9.  Biological study of a nontoxic, water-soluble immunoadjuvant from mycobacterial cell walls.

Authors:  L Chedid; M Parant; F Parant; R H Gustafson; F M Berger
Journal:  Proc Natl Acad Sci U S A       Date:  1972-04       Impact factor: 11.205

10.  Studies on antibody production. IV. The role of a wax fraction of Mycobacterium tuberculosis in adjuvant emulsions on the production of antibody to egg albumin.

Authors:  R G WHITE; A H COONS; J M CONNOLLY
Journal:  J Exp Med       Date:  1955-07-01       Impact factor: 14.307
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  17 in total

1.  Activity in saline of phthalylated or succinylated derivatives of mycobacterial water-soluble adjuvant.

Authors:  F Audibert; L Chedid
Journal:  Infect Immun       Date:  1976-12       Impact factor: 3.441

2.  Modulation of the immune response by a synthetic adjuvant and analogs.

Authors:  L Chedid; F Audibert; P Lefrancier; J Choay; E Lederer
Journal:  Proc Natl Acad Sci U S A       Date:  1976-07       Impact factor: 11.205

3.  Hydrosoluble immunostimulants of bacterial and synthetic origins.

Authors:  P Jollès
Journal:  Experientia       Date:  1976-06-15

Review 4.  Rheumatoid arthritis: review of searches for an infectious cause. Part II.

Authors:  E Wilkes; E S Meek
Journal:  Infection       Date:  1979       Impact factor: 3.553

5.  Preparation of arthritogenic hydrosoluble peptidoglycans from both arthritogenic and non-arthritogenic bacterial cell walls.

Authors:  O Kohashi; C M Pearson; Y Watanabe; S Kotani
Journal:  Infect Immun       Date:  1977-06       Impact factor: 3.441

6.  Immuno-stimulation by a ribosomal vaccine associated with a bacterial cell wall adjuvant in humans.

Authors:  F B Michel; L Dussourd D'Hinterland; J Bousquet; A M Pinel; G Normier
Journal:  Infect Immun       Date:  1978-06       Impact factor: 3.441

7.  Cellular basis of host defence in pyelonephritis. I. Chronic infection.

Authors:  T E Miller; G Findon; S Cawley
Journal:  Br J Exp Pathol       Date:  1986-02

8.  Enhancement of nonspecific immunity to Klebsiella pneumoniae infection by a synthetic immunoadjuvant (N-acetylmuramyl-L-alanyl-D-isoglutamine) and several analogs.

Authors:  L Chedid; M Parant; F Parant; P Lefrancher; J Choay; E Lederer
Journal:  Proc Natl Acad Sci U S A       Date:  1977-05       Impact factor: 11.205

9.  Arthritogenic activity of a synthetic immunoadjuvant, muramyl dipeptide.

Authors:  Z Zídek; K Maśek; Z Jiricka
Journal:  Infect Immun       Date:  1982-02       Impact factor: 3.441

10.  Adjuvant activity of 6-O-acyl-muramyldipeptides to enhance primary cellular and humoral immune responses in guinea pigs: adaptability to various vehicles and pyrogenicity.

Authors:  M Tsujimoto; S Kotani; F Kinoshita; S Kanoh; T Shiba; S Kusumoto
Journal:  Infect Immun       Date:  1986-09       Impact factor: 3.441
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