Literature DB >> 8064769

Drug management of arthritis in the elderly.

A Fleming1.   

Abstract

Rheumatic disorders are common in the ageing population requiring the use of DMARDs and immunosuppressive therapy as with younger patients. Indications for therapy are approximately the same in both groups, but toxic side-effects are probably more common in the elderly necessitating close supervision of indications and drug requirements. Local injection techniques The practice of local injection of corticosteroid in musculo-skeletal disorders is widespread. The literature on comparative efficacy between different preparations is scanty. These techniques can give significant relief in rheumatoid arthritis, osteoarthritis, sero negative arthropathies, crystal induced arthritis and many soft tissue lesions. Severe joint and soft tissue lesions are common in the elderly. In these patients even a small loss of physical function may have a markedly detrimental effect on independence. Such lesions should therefore be actively sought and vigorously treated. Often a simple, rapidly acting, local corticosteroid injection is preferable to a prolonged course of either NSAIDs or physiotherapy. In general, such injections should not be used if the diagnosis is uncertain, or there is any suspicion of infection, or if there has been a previous severe local reaction. Injections that are becoming too regular mean that the technique has not proved successful and other therapies should be sought. In performing the injections, antisepsis should be scrupulous and a 'no-touch' technique used. Accuracy of needle placement is necessary for good results. Injections should not be given against pressure as this generally means incorrect sitting. Some systemic absorption does occur.(ABSTRACT TRUNCATED AT 250 WORDS)

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Year:  1994        PMID: 8064769      PMCID: PMC1294176     

Source DB:  PubMed          Journal:  J R Soc Med        ISSN: 0141-0768            Impact factor:   5.344


  10 in total

Review 1.  Nonsteroidal anti-inflammatory drug gastropathy--is it preventable?

Authors:  P M Brooks; N D Yeomans
Journal:  Aust N Z J Med       Date:  1992-12

Review 2.  Drugs and the elderly.

Authors:  H A Bird
Journal:  Ann Rheum Dis       Date:  1990-12       Impact factor: 19.103

3.  Potential for drug interactions in elderly patients with arthritis.

Authors:  T Hunter
Journal:  Ann Rheum Dis       Date:  1992-07       Impact factor: 19.103

4.  Non-steroidal anti-inflammatory drug usage and requirement in elderly acute hospital admissions.

Authors:  A C Jones; P Berman; M Doherty
Journal:  Br J Rheumatol       Date:  1992-01

5.  Drug interactions in arthritic patients.

Authors:  I E Buchan; H A Bird
Journal:  Ann Rheum Dis       Date:  1991-10       Impact factor: 19.103

Review 6.  Implications of drug therapy in the elderly.

Authors:  J Morgan; D E Furst
Journal:  Clin Rheum Dis       Date:  1986-04

Review 7.  Non-steroidal and analgesic therapy in the elderly.

Authors:  S I Schlegel; H E Paulus
Journal:  Clin Rheum Dis       Date:  1986-04

Review 8.  Side-effects of non-steroidal anti-inflammatory drugs.

Authors:  P M Brooks
Journal:  Med J Aust       Date:  1988-03-07       Impact factor: 7.738

9.  Local injection techniques.

Authors:  A Fleming; J V Bertouch
Journal:  Med J Aust       Date:  1981-05-16       Impact factor: 7.738

Review 10.  Disease-modifying agents and immunosuppressive drugs in the elderly.

Authors:  J W O'Callaghan; P M Brooks
Journal:  Clin Rheum Dis       Date:  1986-04
  10 in total

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