Literature DB >> 8064453

Synovitis in internal derangement of the temporomandibular joint: correlation between arthroscopic and histologic findings.

G W Gynther1, A B Holmlund, F P Reinholt.   

Abstract

PURPOSE: To define arthroscopic criteria for synovitis (SYN) reflecting specific histologic changes. Arthroscopic observations in the temporomandibular joint of patients with internal derangement were compared with histologic patterns in synovial biopsies obtained during arthroscopy. PATIENTS AND METHODS: Arthroscopic biopsies were obtained in 31 joints of 31 patients using an oriented semiblind technique. The histologic changes in the biopsies were compared with those in age-matched reference material obtained at autopsy.
RESULTS: Microscopic examination of the reference material showed inflammation in three specimens (18%), whereas it showed inflammation in 22 patient specimens (71%). Biopsies from the patients also exhibited more pronounced inflammation. According to conventional criteria, arthroscopy showed mild SYN (increased vascularity) in 51%, moderate changes in 39%, and more pronounced changes in 10% of the joints. The presence of moderate or pronounced arthroscopic signs of SYN (capillary hyperemia and synovial hyperplasia), correlated well with the histologic diagnosis of SYN. This was in contrast to patients with mild arthroscopic SYN (increased vascularity).
CONCLUSION: Increased vascularity seen during arthroscopy must be questioned as a sign of SYN. More reliable criteria seem to be capillary hyperemia and synovial hyperplasia.

Entities:  

Mesh:

Year:  1994        PMID: 8064453     DOI: 10.1016/s0278-2391(10)80066-7

Source DB:  PubMed          Journal:  J Oral Maxillofac Surg        ISSN: 0278-2391            Impact factor:   1.895


  7 in total

1.  TRAIL, DR5 and caspase 3-dependent apoptosis in vessels of diseased human temporomandibular joint disc. An immunohistochemical study.

Authors:  C Loreto; L E Almeida; M R Migliore; M Caltabiano; R Leonardi
Journal:  Eur J Histochem       Date:  2010       Impact factor: 3.188

2.  Effect of TLR4/MyD88 signaling pathway on expression of IL-1β and TNF-α in synovial fibroblasts from temporomandibular joint exposed to lipopolysaccharide.

Authors:  Xuefen Lin; Jingjing Kong; Qingting Wu; Yingying Yang; Ping Ji
Journal:  Mediators Inflamm       Date:  2015-02-24       Impact factor: 4.711

3.  Effect of interleukin-1beta and dehydroepiandrosterone on the expression of lumican and fibromodulin in fibroblast-like synovial cells of the human temporomandibular joint.

Authors:  K Okamoto; N Kiga; Y Shinohara; I Tojyo; S Fujita
Journal:  Eur J Histochem       Date:  2015-02-23       Impact factor: 3.188

4.  Effect of Toll-Like Receptor 4 on Synovial Injury of Temporomandibular Joint in Rats Caused by Occlusal Interference.

Authors:  Jingjing Kong; Yingying Yang; Shuzhen Sun; Jianli Xie; Xuefen Lin; Ping Ji
Journal:  Mediators Inflamm       Date:  2016-06-20       Impact factor: 4.711

5.  Toll-Like Receptor 4 (TLR4) Stimulates Synovial Injury of Temporomandibular Joint in Rats Through the Activation of p38 Mitogen-Activated Protein Kinase (MAPK) Signaling Pathway.

Authors:  Xuefen Lin; Jianli Xie; Shuzhen Sun; Xusheng Ren; Jingjing Kong; Ping Ji
Journal:  Med Sci Monit       Date:  2018-06-26

6.  Cytokines in temporomandibular joint synovial fluid and tissue in relation to inflammation.

Authors:  Mattias Ulmner; Rachael Sugars; Aron Naimi-Akbar; Per Alstergren; Bodil Lund
Journal:  J Oral Rehabil       Date:  2022-04-09       Impact factor: 3.558

7.  Screening of bioactive compounds from moutan cortex and their anti-inflammatory activities in rat synoviocytes.

Authors:  Mengjie Wu; Zhiyuan Gu
Journal:  Evid Based Complement Alternat Med       Date:  2007-06-15       Impact factor: 2.629

  7 in total

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