Literature DB >> 8064299

Isolation of antirhinoviral sesquiterpenes from ginger (Zingiber officinale).

C V Denyer1, P Jackson, D M Loakes, M R Ellis, D A Young.   

Abstract

The dried rhizomes of Indonesian ginger, Zingiber officinale, were investigated for antirhinoviral activity in the plaque reduction test. Fractionation by solvent extraction, solvent partition, and repeated chromatography guided by bioassay, allowed the isolation of several sesquiterpenes with antirhinoviral activity. The most active of these was beta-sesquiphellandrene [2] with an IC50 of 0.44 microM vs. rhinovirus IB in vitro.

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Year:  1994        PMID： 8064299     DOI： 10.1021/np50107a017

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  15 in total

1.  Quality attributes, phytochemical profile and storage stability studies of functional ready to serve (RTS) drink made from blend of Aloe vera, sweet lime, amla and ginger.

Authors:  Lokesh K Mishra; Danme Sangma
Journal:  J Food Sci Technol       Date:  2017-02-21       Impact factor: 2.701

Review 2.  A review on antiviral activity of the Himalayan medicinal plants traditionally used to treat bronchitis and related symptoms.

Authors:  Rahila Amber; Muhammad Adnan; Akash Tariq; Sakina Mussarat
Journal:  J Pharm Pharmacol       Date:  2016-12-01       Impact factor: 3.765

3.  Chemopreventive efficacy of ginger (Zingiber officinale) in ethionine induced rat hepatocarcinogenesis.

Authors:  Yasmin Anum Mohd Yusof; Norliza Ahmad; Srijit Das; Suhaniza Sulaiman; Nor Azian Murad
Journal:  Afr J Tradit Complement Altern Med       Date:  2008-10-25

4.  Molecular docking analysis of potential compounds from an Indian medicinal soup "kabasura kudineer" extract with IL-6.

Authors:  S Saleem Basha; Dhirendra Tripathi; Sravanthi Koora; K Satyanarayana; Selvaraj Jayaraman
Journal:  Bioinformation       Date:  2021-05-31

5.  Redifferentiation of human hepatoma cells (SMMC-7721) induced by two new highly oxygenated bisabolane-type sesquiterpenes.

Authors:  Ruidong Miao; Juan Wei; Qi Zhang; Venkateswara Sajja; Jinbo Yang; Qin Wang
Journal:  J Biosci       Date:  2008-12       Impact factor: 1.826

6.  Cytotoxicity and genotoxicity of zingiberene on different neuron cell lines in vitro.

Authors:  Basak Togar; Hasan Turkez; Abdulgani Tatar; Ahmet Hacimuftuoglu; Fatime Geyikoglu
Journal:  Cytotechnology       Date:  2014-05-07       Impact factor: 2.058

7.  Identification of a novel compound (β-sesquiphellandrene) from turmeric (Curcuma longa) with anticancer potential: comparison with curcumin.

Authors:  Amit Kumar Tyagi; Sahdeo Prasad; Wei Yuan; Shiyou Li; Bharat B Aggarwal
Journal:  Invest New Drugs       Date:  2015-11-02       Impact factor: 3.850

8.  Previously published ethno-pharmacological reports reveal the potentiality of plants and plant-derived products used as traditional home remedies by Bangladeshi COVID-19 patients to combat SARS-CoV-2.

Authors:  A T M Rafiqul Islam; Jannatul Ferdousi; Md Shahinozzaman
Journal:  Saudi J Biol Sci       Date:  2021-07-17       Impact factor: 4.219

9.  Overexpressing 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) in the lactococcal mevalonate pathway for heterologous plant sesquiterpene production.

Authors:  Adelene Ai-Lian Song; Janna Ong Abdullah; Mohd Puad Abdullah; Norazizah Shafee; Roohaida Othman; Ee-Fun Tan; Normah Mohd Noor; Abdul Rahim Raha
Journal:  PLoS One       Date:  2012-12-26       Impact factor: 3.240

10.  Synthesis of analogues of gingerol and shogaol, the active pungent principles from the rhizomes of Zingiber officinale and evaluation of their anti-platelet aggregation effects.

Authors:  Hung-Cheng Shih; Ching-Yuh Chern; Ping-Chung Kuo; You-Cheng Wu; Yu-Yi Chan; Yu-Ren Liao; Che-Ming Teng; Tian-Shung Wu
Journal:  Int J Mol Sci       Date:  2014-03-04       Impact factor: 5.923
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